17672-21-8Relevant articles and documents
Oscarellin, an anthranilic acid derivative from a Philippine sponge, Oscarella stillans, as an inhibitor of inflammatory cytokines in macrophages
Kwon, Ii-Seul,Kwak, Jong Hwan,Pyo, Suhkneung,Lee, Hee-Weon,Kim, AeRyon,Schmitz, Francis J.
, p. 149 - 155 (2017)
A new anthranilic acid derivative (1) was isolated from a Philippine sponge, Oscarella stillans (Bergquist and Kelly). The structure of compound 1, named oscarellin, was determined as 2-amino-3-(3′-aminopropoxy)benzoic acid from spectroscopic data and con
Polyheterocyclic substituted pyrimidines or pyridylamine derivatives Composition and medical application thereof
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Paragraph 0258-0260, (2021/09/26)
The invention discloses a polycyclic substituted pyrimidine or pyridine amine derivative, and the structure is shown in a formula (I). The invention further discloses a pharmaceutically acceptable salt of the derivative, a solvate, a stereoisomer, a prodrug, a pharmaceutical composition and and an application thereof in medicine. The compounds of the present invention have significant adenosine A. 2A Receptor and/or adenosine A2B The receptor antagonism activity is very practical.
Anti-Inflammatory and Anti-Diabetic Composition Comprising Novel Compound, Oscarella stillans Extract Containing the Same, or a Fraction Thereof
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Paragraph 0109-0112, (2018/08/30)
The present invention relates to a novel compound, to an extract of Oscarella stillans containing the same, or to an anti-inflammatory and anti-diabetic composition comprising a fraction thereof, wherein the composition exhibits modulatory activity of inf