177174-47-9

Basic information

• Product Name: methyl 2-methoxy-5-(trifluoromethyl)benzoate
• Synonyms: benzoic acid, 2-methoxy-5-(trifluoromethyl)-, methyl ester; Methyl 2-methoxy-5-(trifluoromethyl)benzoate
• CAS NO: 177174-47-9
• Molecular Formula: C₁₀H₉F₃O₃
• Molecular Weight: 234.1719
• Mol File: 177174-47-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 264.699°C at 760 mmHg
• Flash Point: 110.492°C
• Density: 1.267g/cm³
• Vapor Pressure: 0.01mmHg at 25°C
• Refractive Index: 1.45
• CAS DataBase Reference: methyl 2-methoxy-5-(trifluoromethyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-methoxy-5-(trifluoromethyl)benzoate(177174-47-9)
• EPA Substance Registry System: methyl 2-methoxy-5-(trifluoromethyl)benzoate(177174-47-9)

Safety Data

• Hazardous Substances Data: 177174-47-9(Hazardous Substances Data)

Usage

General Description

Methyl 2-methoxy-5-(trifluoromethyl)benzoate, also known as methyl 2-methoxy-5-(trifluoromethyl)benzoate, is a chemical compound that belongs to the class of benzoic acid esters. It is found in the form of a colorless to pale yellow liquid with a sweet, fruity odor. methyl 2-methoxy-5-(trifluoromethyl)benzoate is commonly used in the production of various fragrances and flavors, as well as in the pharmaceutical and agrochemical industries. It is also used as an intermediate in the synthesis of other organic compounds. Methyl 2-methoxy-5-(trifluoromethyl)benzoate is known for its low volatility and stability, making it a valuable ingredient in a wide range of applications. The chemical is considered to have a low potential for bioaccumulation and is not expected to cause harm to the environment when used as directed.

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 402-10-8 2-bromo-1-methoxy-4-(trifluoromethyl)benzene 
• 4864-01-1 2-methoxy-5-(trifluoromethyl)-benzoic acid 
• 22802-67-1 methyl 2-methoxy-5-aminobenzoate 
• 2923-18-4 sodium 2,2,2-trifluoroacetate 
• 40757-09-3 methyl 2-methoxy-5-iodobenzoate 

Downstream Products

• 685126-89-0 (2-methoxy-5-(trifluoromethyl)phenyl)methanol 
• 933982-96-8 2-hydroxy-5-(trifluoromethyl)benzamide 
• 79427-88-6 2-hydroxy-5-(trifluoromethyl)benzoic acid 

Relevant articles and documents

N-(1-CYANO-PYRROLIDIN-3-YL)-5-(3-(TRIFLUOROMETHYL)PHENYL)OXAZOLE-2-CARBOXAMIDE DERIVATIVES AND THE CORRESPONDING OXADIAZOLE DERIVATIVES AS USP30 INHIBITORS FOR THE TREATMENT OF MITOCHONDRIAL DYSFUNCTION

The present invention relates to a class of N-cyanopyrrolidines with activity as inhibitors of the deubiquitylating enzyme USP30, having utility in a variety of therapeutic areas, including conditions involving mitochondrial dysfunction, cancer and fibros

Conversion of aromatic amino into trifluoromethyl groups through a Sandmeyer-type transformation

A novel strategy for aromatic trifluoromethylation by converting amino into trifluoromethyl groups via a Sandmeyer-type reaction is reported. The transformation involves diazotization of the aromatic amines with tert-butyl nitrite and hydrochloric acid to form aryldiazonium chlorides, followed by trifluoromethylation with trifluoromethylsilver at low temperature. Various readily available aromatic amines are smoothly converted under mild conditions. Georg Thieme Verlag Stuttgart. New York.

Melanocortin-4 receptor binding compounds and methods of use thereof

Provided are MC4-R binding compounds of the formula XVII: wherein L2 is a linker group, and P1, P2, P3, P4, Z1, Z2, Z3, Z4, Z5, t, s, and R are a