17742-51-7

Basic information

• Product Name: 4-PHENYLSULFANYL-BUTYRIC ACID
• Synonyms: Butyricacid, 4-(phenylthio)- (6CI,8CI); 4-(Phenylsulfanyl)butanoic acid;4-(Phenylsulfanyl)butyric acid; 4-(Phenylthio)butanoic acid;4-(Phenylthio)butyric acid; NSC 115787; g-(Phenylthio)butyric acid; g-Phenylmercaptobutyric acid
• CAS NO: 17742-51-7
• Molecular Formula: C₁₀H₁₂O₂S
• Molecular Weight: 196.27
• Mol File: 17742-51-7.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 362.9°Cat760mmHg
• Flash Point: 173.3°C
• Appearance: /
• Density: 1.19g/cm³
• Vapor Pressure: 6.65E-06mmHg at 25°C
• CAS DataBase Reference: 4-PHENYLSULFANYL-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PHENYLSULFANYL-BUTYRIC ACID(17742-51-7)
• EPA Substance Registry System: 4-PHENYLSULFANYL-BUTYRIC ACID(17742-51-7)

Safety Data

• Hazardous Substances Data: 17742-51-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12O2S/c11-10(12)7-4-8-13-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)/p-1

Upstream product

• 35756-39-9 4-(phenylthio)butanenitrile 
• 96-48-0 4-butanolide 
• 108-98-5 thiophenol 
• 29193-71-3 methyl 4-(phenylsulfanyl)butanoate 
• 75384-19-9 1-diazo-4-(phenylthio)butan-2-one 
• 4551-15-9 phenylthiotrimethylsilane 
• 4837-01-8 1-bromo-2-phenylthioethane 
• 24536-40-1 3-phenylthiopropanol 
• 3238-98-0 3-phenylthio-1-bromopropane 
• 930-69-8 sodium thiophenolate 
• 1020-68-4 γ-Phenylmercapto-α-carboxy-buttersaeure 
• 625-38-7 but-3-enoic acid 
• 28341-54-0 4-(4-nitrophenoxy)butanoic acid 

Downstream Products

• 1019367-22-6 N-(2-aminophenyl)-4-(phenylsulfanyl)butanamide 
• 1608158-05-9 N-(2-hydroxyphenyl)-4-(phenylsulfanyl)butanamide 
• 29193-71-3 methyl 4-(phenylsulfanyl)butanoate 
• 81331-48-8 4-Phenylsulfanyl-thiobutyric acid S-pyridin-2-yl ester 
• 129518-67-8 (S,S)-N-(2-hydroxy-1-(R)-2-methyl-4-(phenylthio))butan-1-ol 

Relevant articles and documents

CLASS OF HDAC INHIBITORS EXPANDS THE RENAL PROGENITOR CELLS POPULATION AND IMPROVES THE RATE OF RECOVERY FROM ACUTE KIDNEY INJURY

Compounds and compositions are provided that inhibit histone deacylase activity and which expand renal progenitor cell populations and improve kidney function in a damaged kidney. Methods of use of the compounds and compositions are provided.

Synthesis of a wide range of thioethers by indium triiodide catalyzed direct coupling between alkyl acetates and thiosilanes

An indium triiodide-catalyzed substitution of the acetoxy group in alkyl acetates with thiosilanes provides access to a variety of thioethers. The method is efficient for a wide scope of acetates such as primary alkyl, secondary alkyl, tertiary alkyl, allylic, benzylic, and propargylic acetates.

Discovery of Lu AA33810: A highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder

The structure-activity relationship of a series of tricyclic-sulfonamide compounds 11-32 culminating in the discovery of N-[trans-4-(4,5-dihydro-3,6- dithia-1-aza-benzo[e]azulen-2-ylamino)-cyclohexylmethyl]-methanesulfonamide (15, Lu AA33810) is reported. Compound 15 was identified as a selective and high affinity NPY5 antagonist with good oral bioavailability in mice (42%) and rats (92%). Dose dependent inhibition of feeding was observed after i.c.v. injection of the selective NPY5 agonist ([cPP1-7,NPY19-23,Ala 31,Aib32,Gln34]-hPP). In addition, ip administration of Lu AA33810 (10 mg/kg) produced antidepressant-like effects in a rat model of chronic mild stress.