17751-50-7

Basic information

• Product Name: N-ethyl-N-(pyridin-2-ylmethyl)ethanamine
• Synonyms: 2-Pyridinemethanamine, N,N-diethyl-
• CAS NO: 17751-50-7
• Molecular Formula: C₁₀H₁₆N₂
• Molecular Weight: 164.2474
• Mol File: 17751-50-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 214.4°C at 760 mmHg
• Flash Point: 83.5°C
• Density: 0.953g/cm³
• Vapor Pressure: 0.156mmHg at 25°C
• Refractive Index: 1.509
• CAS DataBase Reference: N-ethyl-N-(pyridin-2-ylmethyl)ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-ethyl-N-(pyridin-2-ylmethyl)ethanamine(17751-50-7)
• EPA Substance Registry System: N-ethyl-N-(pyridin-2-ylmethyl)ethanamine(17751-50-7)

Safety Data

• Hazardous Substances Data: 17751-50-7(Hazardous Substances Data)

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 109-89-7 diethylamine 
• 109-04-6 2-bromo-pyridine 
• 24244-60-8 2-(phenylsulfonyl)pyridine 
• 10545-36-5 N-<(trimethylsilyl)methyl>-N,N-diethylamine 
• 6959-47-3 2-chloromethylpyridine hydrochloride 
• 74-86-2 acetylene 
• 3010-02-4 diethylaminoacetonitrile 

Downstream Products

• 123839-86-1 N-ethyl-N-(phenyl(pyridin-2-yl)methyl)ethanamine 

Relevant articles and documents

Metal-Free Aminomethylation of Aromatic Sulfones Promoted by Eosin Y

A metal-free α-aminomethylation of heteroaryls promoted by eosin Y under green light irradiation is reported. A large variety of α-trimethylsilylamines as precursor of α-aminomethyl radical species were engaged to functionalize sulfonyl-heteroaryls following a Homolytic Aromatic Substitution (HAS) pathway. This method has provided a range of α-aminoheteroaryl compounds including a functionalized natural product. The mechanism of this late-stage functionalization of aryls was investigated and suggests the formation of a sulfonyl radical intermediate over a reductive quenching cycle.

Simple Metal-Free Direct Reductive Amination Using Hydrosilatrane to Form Secondary and Tertiary Amines

This work describes the use of cheap, safe, and easy-to-handle hydrosilatrane as the reductant in direct reductive amination reactions. This efficient method enables a facile, metal-free access to secondary and tertiary amines from a wide range of aldehydes and ketones, with the synthesis of tertiary amines requiring no additives at all. This reaction demonstrates excellent functional group tolerance, chemoselectivity, and scalability. (Figure presented.).

Synthesis, structures of (aminopyridine)nickel complexes and their use for catalytic ethylene polymerization

A series of α-aminopyridines in the form of (2,6-C6H 3N)(R1)(CHR2NR3R4) (R1 = R2 = H R3 = H R4 = iPr (L1a), R4 = tBu (L1b), R4 = Ph (L1c), R4 = 2,6-Me2C6H3 (L1d), R4 = 2,6-iPr2C6H3 (L1e), R1 = R2 = H R3 = R4 = Et (L1f), R1 = H R2 = Me R3 = H R4 = iPr (L2a), R4 = Ph (L2c), R4 = 2,6-Me 2C6H3 (L2d), R4 = 2,6- iPr2C6H3 (L2e), R1 = Me R2 = H R3 = H R4 = 2,6-iPr 2C6H3 (L3e)) and β-aminopyridines in the form of (2-C6H4N)(CH2CH2NR 1R2) (R1 = H R2 = iPr (4a), R2 = tBu (L4b), R1 = R2 = Et (L4f)) have been prepared. Their corresponding halonickel complexes 1a-4f are synthesized by ligand substitution from (DME)NiBr2 and the molecular structures are characterized. Four types of coordination modes include four-coordinate mononuclear species with one ligand, five-coordinate mononuclear species with two ligands, five-coordinate dinuclear species with two ligands, and a six-coordinate polymeric framework were determined by X-ray crystallography. Using methylaluminoxanes (MAO) as the activator, the nickel complexes can catalyze ethylene polymerization under moderate pressure and ambient temperature. The activity reaches 105 g PE mol-1 Ni h. The PE products with high branching and high crystallinity have M n ～ 103 with PDI 2.