17776-78-2

Basic information

• Product Name: BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE
• Synonyms: BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE
• CAS NO: 17776-78-2
• Molecular Formula: C₁₂H₈Cl₃O₃P
• Molecular Weight: 337.52
• Mol File: 17776-78-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 184-186°C 0,4mm
• Flash Point: 184-186°C/0.4mm
• Appearance: /
• Density: 1.465
• Vapor Pressure: 5.82E-07mmHg at 25°C
• Refractive Index: 1.5705
• Sensitive: Moisture Sensitive
• BRN: 2152478
• CAS DataBase Reference: BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE(17776-78-2)
• EPA Substance Registry System: BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE(17776-78-2)

Safety Data

• Statements: 34
• Safety Statements: 26-36/37/39
• RIDADR: 3265
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 17776-78-2(Hazardous Substances Data)

Usage

General Description

BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE is a chemical compound with the formula C12H8Cl4O2P. It is commonly used as an intermediate in the synthesis of pesticides and insecticides. BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE is classified as a chlorophenyl phosphorochloridate, which means it contains chlorophenyl groups attached to a phosphorus atom. BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE is highly toxic and can cause severe irritation and damage to the skin, eyes, and respiratory system. It should be handled with extreme caution and proper protective equipment.

InChI:InChI=1/C12H8Cl3O3P/c13-9-5-1-3-7-11(9)17-19(15,16)18-12-8-4-2-6-10(12)14/h1-8H

Upstream product

• 24460-31-9 tri-(2-chlorophenyl) phosphite 
• 95-57-8 2-monochlorophenol 
• 65475-24-3 phosphonic acid bis-(2-chloro-phenyl ester) 

Downstream Products

• 116295-51-3 phosphoric acid bis-(2-chloro-phenyl ester)-(4-cyclohexyl-phenyl ester) 
• 115752-41-5 (4-Amino-3-nitro-phenyl)-phosphoramidic acid bis-(2-chloro-phenyl) ester 
• 86670-59-9 Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(3,5-dimethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester bis-(2-chloro-phenyl) ester 
• 93180-03-1 Phosphoric acid bis-(2-chloro-phenyl) ester (3aR,4R,6aR)-2,2-dimethyl-6-(3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 89539-19-5 Bis(o-chlorophenyl) 5'-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine 3'-phosphate 
• 116992-74-6 bis(2-chlorophenyl)amidophosphate 
• 93180-04-2 Phosphoric acid (3aR,4R,6R,6aR)-6-(6-amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester bis-(2-chloro-phenyl) ester 
• 78098-68-7 2',3',5'-tri-O-acetyl-N⁶-methyl-N⁶-bis-o-chlorophenylphosphoryladenosine 
• 78098-67-6 2',3',5'-tri-O-acetyl-N⁶-bis-o-chlorophenylphosphoryl-adenosine 
• 89539-17-3 Bis(o-chlorophenyl) 5'-O-(tert-butyldimethylsilyl)-2'-deoxycytidine 3'-phosphate 
• 36400-49-4 phosphoric acid bis-(2-chloro-phenyl ester) 
• 1021947-61-4 bis(2-chlorophenyl)N-hexyl phosphoramidate 
• 1021947-64-7 butyl 2-chlorophenyl ethylphosphonate 
• 1021947-60-3 butyl bis(2-chlorophenyl) phosphate 

Relevant articles and documents

A new approach to the synthesis of oligonucleotides and their phosphorothioate analogues in solution

A new approach to the synthesis of oligonucleotides and oligonucleotide phosphorothioates in solution is described; it is based on H-phosphonate coupling at -40°, followed by in situ sulfur-transfer with either N-[(4-chlorophenyl)sulfanyl]phthalimide 19 o

SUBSTITUTED PHOSPHORYLAMIDOPHOSPHATES

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