17776-78-2

Usage

Uses

Used in Pesticide and Insecticide Synthesis:
BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE is utilized as an intermediate in the production of various pesticides and insecticides. Its chemical properties make it a valuable component in the synthesis of these agricultural and household products, contributing to their effectiveness in controlling pests and insects.
Used in Chemical Research:
In the field of chemical research, BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE serves as a subject of study for understanding the properties and reactions of chlorophenyl phosphorochloridate compounds. This research can lead to the development of new applications and improvements in existing products that incorporate BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE may also have potential applications in the pharmaceutical industry as a starting material for the synthesis of certain pharmaceutical compounds. Its unique structure and reactivity could be harnessed to create new drugs or improve existing ones.

InChI:InChI=1/C12H8Cl3O3P/c13-9-5-1-3-7-11(9)17-19(15,16)18-12-8-4-2-6-10(12)14/h1-8H

Upstream product

• 65475-24-3 phosphonic acid bis-(2-chloro-phenyl ester) 
• 95-57-8 2-monochlorophenol 
• 24460-31-9 tri-(2-chlorophenyl) phosphite 

Downstream Products

• 116295-51-3 phosphoric acid bis-(2-chloro-phenyl ester)-(4-cyclohexyl-phenyl ester) 
• 115752-41-5 (4-Amino-3-nitro-phenyl)-phosphoramidic acid bis-(2-chloro-phenyl) ester 
• 86670-59-9 Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(3,5-dimethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester bis-(2-chloro-phenyl) ester 
• 93180-03-1 Phosphoric acid bis-(2-chloro-phenyl) ester (3aR,4R,6aR)-2,2-dimethyl-6-(3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 89539-19-5 Bis(o-chlorophenyl) 5'-O-(tert-butyldimethylsilyl)-2'-deoxyguanosine 3'-phosphate 
• 116992-74-6 bis(2-chlorophenyl)amidophosphate 
• 93180-04-2 Phosphoric acid (3aR,4R,6R,6aR)-6-(6-amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester bis-(2-chloro-phenyl) ester 
• 93198-83-5 Phosphoric acid (2R,3S,5R)-5-(6-amino-purin-9-yl)-3-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-furan-2-ylmethyl ester bis-(2-chloro-phenyl) ester 
• 84927-08-2 bis(o-chlorophenyl) 5'-O-(tert-butyldimethylsilyl)-2'-deoxyadenosine 3'-phosphate 
• 78098-68-7 2',3',5'-tri-O-acetyl-N⁶-methyl-N⁶-bis-o-chlorophenylphosphoryladenosine 
• 78098-67-6 2',3',5'-tri-O-acetyl-N⁶-bis-o-chlorophenylphosphoryl-adenosine 
• 84915-25-3 Bis(o-chlorophenyl) 5'-O-(tert-butyldimethylsilyl)thymidine 3'-phosphate 
• 89539-17-3 Bis(o-chlorophenyl) 5'-O-(tert-butyldimethylsilyl)-2'-deoxycytidine 3'-phosphate 
• 115752-30-2 {5-[Bis-(2-chloro-phenoxy)-phosphorylamino]-1H-benzoimidazol-2-yl}-carbamic acid methyl ester 

Relevant academic research and scientific papers

A new approach to the synthesis of oligonucleotides and their phosphorothioate analogues in solution

A new approach to the synthesis of oligonucleotides and oligonucleotide phosphorothioates in solution is described; it is based on H-phosphonate coupling at -40°, followed by in situ sulfur-transfer with either N-[(4-chlorophenyl)sulfanyl]phthalimide 19 o

Hydrogen phosphates: Self initiated organocatalysts for the controlled ring-opening polymerization of cyclic esters

A series of arylhydrogenphosphates and aryldihydrogenphosphates was synthesized and characterized using spectroscopic methods and single crystal X-ray diffraction. These compounds were assessed as catalysts towards the ring-opening polymerization and proved to be potent organocatalysts for the ring-opening polymerization of cyclic esters. The bulk polymerizations were performed in the absence of external initiator. The polymerization proceeds in a controlled fashion which leads to well defined polyesters with narrow molecular weight distributions. In the post polymerization experiments, kinetics, mechanism and monomer concentration effects were investigated. The kinetic results have confirmed the pseudo-living character of the polymerizations and mechanistic studies suggest that the polymerization operates through a cationic mechanism.