Bis(2-chlorophenyl) phosphorochloridate

Base Information

• Chemical Name: Bis(2-chlorophenyl) phosphorochloridate
• CAS No.: 17776-78-2
• Molecular Formula: C12H8 Cl3 O3 P
• Molecular Weight: 337.526
• DSSTox Substance ID: DTXSID40402367
• Nikkaji Number: J1.144.823B
• Mol file: 17776-78-2.mol

Synonyms:17776-78-2;BIS(2-CHLOROPHENYL) PHOSPHOROCHLORIDATE;1-chloro-2-[chloro-(2-chlorophenoxy)phosphoryl]oxybenzene;Bis(2-chlorophenyl)phosphorochloridate;bis(2-chlorophenyl)chlorophosphate;Phosphorochloridic acid, bis(2-chlorophenyl) ester;bis-(2-chlorophenyl)phosphorochloridate;SCHEMBL1070126;DTXSID40402367;bis(2-chlorophenyl) chlorophosphate;Bis(2-chlorophenyl)phosphorchloridate;MFCD00015736;AKOS016025246;AS-68618;FT-0623000;Chloridophosphoric acid bis(2-chlorophenyl) ester

Chemical Property of Bis(2-chlorophenyl) phosphorochloridate

Chemical Property:

• Vapor Pressure: 5.82E-07mmHg at 25°C
• Refractive Index: 1.5705
• Boiling Point: 422.7°Cat760mmHg
• Flash Point: 332.8°C
• PSA: 45.34000
• Density: 1.501g/cm³
• LogP: 5.79810
• Sensitive.: Moisture Sensitive
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 335.927664
• Heavy Atom Count: 19
• Complexity: 314

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s): R34:Causes burns.
• Hazard Codes: R34:Causes burns.
• Statements: 34
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)OP(=O)(OC2=CC=CC=C2Cl)Cl)Cl

Technology Process of Bis(2-chlorophenyl) phosphorochloridate

There total 4 articles about Bis(2-chlorophenyl) phosphorochloridate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-monochlorophenol (95-57-8) → bis(2-chlorophenyl) chlorophosphate (17776-78-2)

Guidance literature:

With trichlorophosphate; Heating;

DOI:10.1016/S0960-894X(97)10073-7

Reference yield:

phosphonic acid bis-(2-chloro-phenyl ester) (65475-24-3) → bis(2-chlorophenyl) chlorophosphate (17776-78-2)

Guidance literature:

With sulfuryl dichloride; chlorine;

DOI:10.1021/ja01521a028

Reference yield:

tri-(2-chlorophenyl) phosphite (24460-31-9) → bis(2-chlorophenyl) chlorophosphate (17776-78-2)

Guidance literature:

Multi-step reaction with 2 steps

1: phosphonic acid

2: chlorine; tetrachloromethane

With tetrachloromethane; phosphonic acid; chlorine;

DOI:10.1021/ja01521a028

upstream raw materials:

phosphonic acid bis-(2-chloro-phenyl ester)

2-monochlorophenol

tri-(2-chlorophenyl) phosphite

Downstream raw materials:

phosphoric acid bis-(2-chloro-phenyl ester)-(4-cyclohexyl-phenyl ester)

(4-Amino-3-nitro-phenyl)-phosphoramidic acid bis-(2-chloro-phenyl) ester

Phosphoric acid (2R,3S,5R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-5-(3,5-dimethyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester bis-(2-chloro-phenyl) ester

Phosphoric acid bis-(2-chloro-phenyl) ester (3aR,4R,6aR)-2,2-dimethyl-6-(3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester

Refernces

• 1、 Malik, Payal,Chakraborty, Debashis. "Hydrogen phosphates: Self initiated organocatalysts for the controlled ring-opening polymerization of cyclic esters". . p. 32 - 41. Retrieved 2013/07/19.