17781-86-1

Basic information

• Product Name: n-butyl-anthranilicaci
• Synonyms: n-butyl-anthranilicaci;Benzoic acid,2-(butylaMino)-
• CAS NO: 17781-86-1
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.245
• Mol File: 17781-86-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 346.7°Cat760mmHg
• Flash Point: 163.5°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 2.14E-05mmHg at 25°C
• CAS DataBase Reference: n-butyl-anthranilicaci(CAS DataBase Reference)
• NIST Chemistry Reference: n-butyl-anthranilicaci(17781-86-1)
• EPA Substance Registry System: n-butyl-anthranilicaci(17781-86-1)

Safety Data

• Hazardous Substances Data: 17781-86-1(Hazardous Substances Data)

Usage

General Description

n-butyl-anthranilic acid is a chemical compound with the molecular formula C16H17NO2. It is commonly used as an intermediate in the production of various organic compounds and is also used as a fragrance ingredient in the cosmetics and personal care industry. n-butyl-anthranilic acid is known for its musky, floral odor and is often used in perfumes and colognes. It is also used as a flavoring agent in food and beverages. This chemical is considered to be relatively safe for use in these applications, but proper handling and storage procedures should be followed to ensure safety.

InChI:InChI=1/C11H15NO2/c1-2-3-8-12-10-7-5-4-6-9(10)11(13)14/h4-7,12H,2-3,8H2,1H3,(H,13,14)/p-1

Upstream product

• 109-73-9 N-butylamine 
• 118-91-2 ortho-chlorobenzoic acid 
• 109-69-3 n-Butyl chloride 
• 118-92-3 anthranilic acid 
• 109-65-9 1-bromo-butane 

Relevant articles and documents

Development of Quinazoline/Pyrimidine-2,4(1H,3H)-diones as Agonists of Cannabinoid Receptor Type 2

Starting from a prototypical structure 1, we describe our efforts to design and obtain novel quinazoline/pyrimidine-2,4(1H,3H)-diones with high CB2 agonist potency and selectivity as well as improved physicochemical characteristics, mainly hydrophilicity. The most potent and selective CB2 agonists, 8 and 36, in this series were also endowed with lower logP values than that of GW842166X and lead compound 1. These derivatives appear to be promising lead compounds for the development of future CB2 agonists.

Ultrasound-promoted reaction of 2-chlorobenzoic acids and aliphatic amines

An improvement to the use of DMF as a solvent for the condensation of 2-chlorobenzoic acids with aliphatic primary or secondary amines was described. A number of alkylaminobenzoic acids and dialkylaminobenzoic acids were synthesized in acceptable-to-good yield. The advantages of this procedure include readily available substrates, the use of an inexpensive copper powder without taking any precautions to exclude moisture under mild conditions and experimental ease. Furthermore, this condensation could also be achieved under nonclassical conditions by using ultrasonic irradiation at room temperature. We demonstrated that ultrasound-promoted condensation of 2-chlorobenzoic acid with aliphatic amines with the use of DMF as the solvent, especially in the case of secondary amines, affords products in high yields and reduces the reaction time to minutes. The results proved to be highly reproducible because the relevant sonochemical parameters were rigorously controlled. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.

Synthesis, biological data and correlation analysis in a set of analgesic drugs

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