17792-18-6

Upstream product

• 75-44-5 phosgene 
• 4356-69-8 1,1-bis-(4-methoxyphenyl)ethylene 
• 79-37-8 oxalyl dichloride 
• 71-43-2 benzene 
• 66110-26-7 3,3-bis(4-methoxyphenyl)pentanedioic acid 
• 100-66-3 methoxybenzene 
• 100-09-4 4-methoxybenzoic acid 
• 31892-99-6 ethyl 3,3-bis(4'-methoxyphenyl)prop-2-enoate 
• 19618-37-2 3,3-Bis-(4'-methoxyphenyl)propenal 
• 90-96-0 bis(p-methoxyphenyl)methanone 
• 79564-33-3 3,3-bis(4-methoxyphenyl)pentanedioic acid anhydride 
• 94905-41-6 4,4-bis-(4-methoxy-phenyl)-2-oxo-but-3-enenitrile 
• 102162-83-4 3-hydroxy-3,3-bis-(4-methoxy-phenyl)-propionic acid ethyl ester 
• 98921-99-4 bis(4-acyl phenyl) cinnamic acid methyl ester 

Downstream Products

• 115499-61-1 N-benzyl-3,3-bis(4-methoxyphenyl)acrylamide 
• 1227857-57-9 N-tosyl-3,3-bis(4-methoxyphenyl)acrylamide 
• 1439401-68-9 3,3-bis(4-methoxyphenyl)-N-methyl-N-phenylacrylamide 
• 2132-62-9 4,4'-dimethoxydiphenylacetylene 
• 528852-24-6 2,2-di-(p-methoxyphenyl)-phenanthro-(9,10)-[2H]-[1,4]-oxazine 
• 133262-42-7 1-[3,3-Bis(4-methoxyphenyl)acryloyl]-4-[3,4,5-trimethoxy(thiobenzoyl)]piperazine 
• 133261-85-5 1-[3,3-Bis(4-methoxyphenyl)acryloyl]-4-(3,4,5-trimethoxybenzoyl)piperazine 
• 133263-92-0 1-[3,3-bis(4-methoxyphenyl)acryloyl]piperazine 
• 4356-69-8 1,1-bis-(4-methoxyphenyl)ethylene 
• 800382-45-0 1,1-[bis(4-methoxyphenyl)]-2-(4-nitro-phenyl)ethene 
• 92241-60-6 4,4'-[2-(p-tolyl)ethene-1,1-diyl]bis(methoxybenzene) 
• 2132-70-9 1,1-dichloro-2,2-bis(p-methoxyphenyl)ethylene 
• 35582-69-5 bis-3,3-(p-methoxyphenyl)-propionic acid 

Relevant academic research and scientific papers

A Weinreb Amide Based Building Block for Convenient Access to β,β-Diarylacroleins: Synthesis of 3-Arylindanones

Towards the synthesis of symmetrical and unsymmetrical β,β-diarylacroleins for assembling diarylmethine fragments present in biologically important molecules, we have developed a new Weinreb amide (WA) based building block, derived from propiolic acid. The WA functionality present in this compound allowed the sequential addition of various arylmagnesium bromide reagents in a controlled manner. The developed methodology for the access to β,β-diarylacroleins has been utilised for the synthesis of biologically important 3-arylindanone molecules. Synthesis of both symmetrical and unsymmetrical β,β-diarylacrolein and diarylmethine fragments, have been achieved via easily accessible and hitherto unknown Weinreb Amide (WA) based building block 11. The WA functionality allowed the sequential addition of nucleophiles such as arylmagnesium bromide in a controlled manner, which has enabled the synthesis of an important 3-arylindanone molecule.

Synthesis of coumarins via PIDA/I2-mediated oxidative cyclization of substituted phenylacrylic acids

A variety of functionalized coumarins were synthesized from substituted phenylacrylic acids via PIDA/I2-mediated and irradiation-promoted oxidative carbon-oxygen bond formation. Our studies show that the oxygen in the pendant carboxylic acid group cyclizes favorably to the aryl ring that is cis to it. The main advantages of this method include good functional group tolerance and the transition-metal-free characteristic. The Royal Society of Chemistry 2013.

Palladium-catalyzed intramolecular amidation of C(sp2)-H bonds: Synthesis of 4-aryl-2-quinolinones

Figure presented A catalytic synthetic approach for the synthesis of 2-quinolinone compounds through a Pd-catalyzed C(sp2)-H functionalization/intramolecular amidation sequence is described. The cyclization process efficiently proceeds in the p

Decarboxylative Cleavage During Friedel-Crafts Reaction of 3,3-Diarylpentanedioic Anhydride with Anisole

Treatment of acetonedicarboxylic acid with excess aryl ethers gives 3,3-diarylpentanedioic acids in good yields. 3,3-Diarylpentanedioic anhydrides (VII) on the Friedel-Crafts reaction with aryl ethers in the presence of AlCl3 in nitrobenzene give a mixture of 3,3-diarylpropenoic acids (X) and 1,1-diarylethenes (IX) instead of the normal product, 3,3-diaryl-4-aroylbutanoic acid.