178211-34-2

Upstream product

• 6683-57-4 4,5-Dimethoxy-2-(4-methoxy-benzoyl)-benzoic acid 
• 122365-23-5 N-[(diphenylphosphinoyl)methyl]-N-methylamine 
• 4821-94-7 4,5-dimethoxyphthalic anhydride 
• 100-66-3 methoxybenzene 

Downstream Products

• 75327-46-7 cherylline lactam 
• 26996-80-5 4-(4-hydroxyphenyl)-7-hydroxy-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 23330-76-9 6,7-dimethoxy-4-(4-methoxyphenyl)-2-methyl-1, 2, 3, 4-tetrahydroisoquinoline 
• 110841-23-1 6,7-dimethoxy-4-(4-methoxyphenyl)-2-methyl-2H-isoquinolin-1-one 

Relevant academic research and scientific papers

Base-induced cyclization of trimethoxy-o-aroyldiphenylphosphoryl methylbenzamide: A formal synthesis of (±)Cherylline and (±)Cherylline dimethylether

The trimethoxy-o-aroyldiphenylphosphorylmethylbenzamide 9 can be cyclized by treatment with KHMDS; the procedure has been employed to synthesize (±)Cherylline 1 and its dimethylether 2.