110841-23-1

Upstream product

• 4821-94-7 4,5-dimethoxyphthalic anhydride 
• 100-66-3 methoxybenzene 
• 103477-58-3 2-(2-bromo-4,5-dimethoxyphenyl)-1,3-dioxolane 
• 110841-28-6 α-2-<(1,3-dioxolan-2-yl)-4,5-dimethoxyphenyl>-4-methoxybenzyl alcohol 
• 110841-26-4 4,5-Dimethoxy-2-(4-methoxy-benzyl)-N-methyl-benzamide 
• 6683-57-4 4,5-Dimethoxy-2-(4-methoxy-benzoyl)-benzoic acid 
• 178211-34-2 N-(Diphenyl-phosphinoylmethyl)-4,5-dimethoxy-2-(4-methoxy-benzoyl)-N-methyl-benzamide 
• 110841-25-3 3-Hydroxy-6,7-dimethoxy-4-(4-methoxy-phenyl)-2-methyl-3,4-dihydro-2H-isoquinolin-1-one 

Downstream Products

• 75327-46-7 cherylline lactam 
• 26996-80-5 4-(4-hydroxyphenyl)-7-hydroxy-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 23330-76-9 6,7-dimethoxy-4-(4-methoxyphenyl)-2-methyl-1, 2, 3, 4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

Novel methods for the synthesis of 4-arylisoquinolinium perchlorates and 4-arylisoquinolin-1-ones

2-Benzylamino-1-phenyl-ethanones 1 were converted to the corresponding isoquinolinium perchlorates 2 in high yields using 70% HClO4- FeCl3 mixture as a cyclization and oxidation reagent. A mild and high yielding method for the oxidat

Base-induced cyclization of trimethoxy-o-aroyldiphenylphosphoryl methylbenzamide: A formal synthesis of (±)Cherylline and (±)Cherylline dimethylether

The trimethoxy-o-aroyldiphenylphosphorylmethylbenzamide 9 can be cyclized by treatment with KHMDS; the procedure has been employed to synthesize (±)Cherylline 1 and its dimethylether 2.

An Efficint Synthesis of 4-Aryl-1,2,3,4-terahydroisoquinolines

A general synthesis of N-methyl-1,2,3,4-tetrahydroisoquinolines from 3-aryl phthalides is described.