178233-18-6

Basic information

• Product Name: 7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-5-methyl-4-oxo-q uinoline-3-carboxylic acid
• Synonyms: 7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-5-methyl-4-oxo-q uinoline-3-carboxylic acid
• CAS NO: 178233-18-6
• Molecular Formula: C18H19F2N3O3
• Molecular Weight: 0
• Mol File: 178233-18-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 604°Cat760mmHg
• Flash Point: 319.1°C
• Appearance: /
• Density: 1.507g/cm³
• Vapor Pressure: 1.94E-15mmHg at 25°C
• Refractive Index: 1.653
• CAS DataBase Reference: 7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-5-methyl-4-oxo-q uinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-5-methyl-4-oxo-q uinoline-3-carboxylic acid(178233-18-6)
• EPA Substance Registry System: 7-(3-aminopyrrolidin-1-yl)-1-cyclopropyl-6,8-difluoro-5-methyl-4-oxo-q uinoline-3-carboxylic acid(178233-18-6)

Safety Data

• Hazardous Substances Data: 178233-18-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C18H19F2N3O3/c1-8-12-15(14(20)16(13(8)19)22-5-4-9(21)6-22)23(10-2-3-10)7-11(17(12)24)18(25)26/h7,9-10H,2-6,21H2,1H3,(H,25,26)

Upstream product

• 79286-79-6 pyrrolidin-3-amine 
• 119915-54-7 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-5-methyl-4-oxo-3-quinolinecarboxylic acid 
• 99724-19-3 3-(tert-butoxycarbonylamino)pyrrolidine 

Relevant articles and documents

Synthesis and Biological Activity of 5-Alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic Acids

A series of 5-alkyl-1,7,8-trisubstituted-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was prepared and evaluated for in vitro and in vivo antibacterial activity.When compared to the 5-hydrogen analogues, the presence of the 5-methyl group enhanc

Antibacterial agents

Novel naphthyridine-, and quinolinecarboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediates used in the