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(R)-2-benzyloxy-2-methylmalonic acid monoethyl ester is a chiral organic compound with the molecular formula C13H16O5. It is a derivative of malonic acid, featuring a benzyloxy group at the 2-position and a methyl group at the 2-carbon, with an ethyl ester group attached to the carboxylic acid functionality. (R)-2-benzyloxy-2-methylmalonic acid monoethyl ester is significant in organic synthesis, particularly in the preparation of chiral building blocks and pharmaceutical intermediates. Its stereochemistry is defined by the R-configuration at the 2-carbon, which is crucial for its reactivity and potential applications in the synthesis of enantiomerically pure compounds. The compound's structure and properties make it a valuable tool in the field of asymmetric synthesis and drug development.

1786-91-0

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1786-91-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1786-91-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,8 and 6 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1786-91:
(6*1)+(5*7)+(4*8)+(3*6)+(2*9)+(1*1)=110
110 % 10 = 0
So 1786-91-0 is a valid CAS Registry Number.

1786-91-0Relevant academic research and scientific papers

Asymmetric synthesis of (R)-(-)-chlozolinate through a chemoenzymatic procedure

Guanti, Giuseppe,Banfi, Luca,Powles, Katharine,Rasparini, Marcello,Scolastico, Carlo,Fossati, Novella

, p. 271 - 277 (2001)

A new asymmetric synthesis of (R)-chlozolinate 1, an important antifungal agent, based on the enzymatic asymmetrization of diethyl 2-benzyloxy-2-methylmalonate, is reported.

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