17869-76-0

Basic information

• Product Name: 2-TRIMETHYLSILYLOXY-3-BUTYNE
• Synonyms: 3-(TRIMETHYLSILOXY)-1-BUTYNE;3-(TRIMETHYLSILYLOXY)-1-BUTYNE;2-TRIMETHYLSILOXY-3-BUTYNE;2-TRIMETHYLSILYLOXY-3-BUTYNE;TIMTEC-BB SBB009059;(1-Methyl-2-propynyl)(trimethylsilyl) ether;(1-Methyl-2-propynyloxy)trimethylsilane;3-(Trimethylsiloxy)-3-methyl-1-propyne
• CAS NO: 17869-76-0
• Molecular Formula: C₇H₁₄OSi
• Molecular Weight: 142.27
• Mol File: 17869-76-0.mol
• Article Data: 11

Chemical Properties

• Melting Point: 127-131 °C(lit.)
• Boiling Point: 116 °C
• Flash Point: 42 °F
• Appearance: clear pale yellow liquid
• Density: 0.818 g/mL at 25 °C(lit.)
• Vapor Pressure: 23.5mmHg at 25°C
• Refractive Index: n20/D 1.405(lit.)
• Storage Temp.: Refrigerator (+4°C)
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 2-TRIMETHYLSILYLOXY-3-BUTYNE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-TRIMETHYLSILYLOXY-3-BUTYNE(17869-76-0)
• EPA Substance Registry System: 2-TRIMETHYLSILYLOXY-3-BUTYNE(17869-76-0)

Safety Data

• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-26
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• TSCA: No
• HazardClass: 3
• Hazardous Substances Data: 17869-76-0(Hazardous Substances Data)

Usage

Chemical Properties

Clear pale yellow liquid

InChI:InChI=1/C7H14OSi/c1-6-7(2)8-9(3,4)5/h1,7H,2-5H3

Upstream product

• 2028-63-9 but-3-yn-2-ol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 75-77-4 chloro-trimethyl-silane 
• 1067-35-2 triethyl-(1-methyl-prop-2-ynyloxy)-stannane 

Downstream Products

• 205172-19-6 (1R,4R,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,2,6-trimethyl-1-((E)-3-trimethylsilanyloxy-but-1-enyl)-cyclohexanol 
• 205172-20-9 (1S,4R,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,2,6-trimethyl-1-((E)-3-trimethylsilanyloxy-but-1-enyl)-cyclohexanol 
• 1345828-52-5 1,3,5-tris(1-(trimethylsilyloxy)ethyl)benzene 
• 1345828-54-7 1,2,4-tris(1-(trimethylsilyloxy)ethyl)benzene 
• 103253-60-7 4-trimethylsilyl-3-butyn-2-ol 

Relevant articles and documents

[3,3]-Sigmatropic rearrangement of boronated allylcyanates: A new route to α-aminoboronate derivatives and trisubstituted tetrahydrofurans

[3,3]-Sigmatropic cyanate-isocyanate rearrangement provides a powerful tool for the preparation of α-isocyanato allylboronic esters, which can be further trapped with a variety of nucleophiles. Hydrogenation gave the corresponding α-aminoboronates derivatives while addition of aldehydes afforded homoallylic alcohols, (tetrahydrofuran-2-yl)carbamate, ether, or urea derivatives.

Mild and efficient silylation of alcohols and phenols with HMDS using Bi(OTf)3 under solvent-free condition

A very efficient and mild silylation of alcohols and phenols with hexamethyldisilazane (HMDS) at rt is developed using Bi(OTf)3 as the catalyst. Primary, secondary and tertiary alcohols as well as phenols are excellently converted into correspo

Silylation of hydroxy groups with HMDS under microwave irradiation and solvent-free conditions

Phenols and alcohols are silylated with hexamethyldisilazane (HMDS) under microwave irradiation in solvent-free condition in good to excellent yields.