3-(Trimethylsilyloxy)-1-butyne

Base Information

• Chemical Name: 3-(Trimethylsilyloxy)-1-butyne
• CAS No.: 17869-76-0
• Molecular Formula: C₇H₁₄OSi
• Molecular Weight: 142.273
• Hs Code.: 29310099
• European Community (EC) Number: 625-502-2
• DSSTox Substance ID: DTXSID00939109
• Nikkaji Number: J142.879I
• Mol file: 17869-76-0.mol

Synonyms:17869-76-0;3-(Trimethylsilyloxy)-1-butyne;2-Trimethylsilyloxy-3-butyne;but-3-yn-2-yloxy(trimethyl)silane;(but-3-yn-2-yloxy)trimethylsilane;Silane, trimethyl[(1-methyl-2-propynyl)oxy]-;Silane, trimethyl[(1-methyl-2-propyn-1-yl)oxy]-;3-Butyn-2-ol, TMS derivative;2-TRIMETHYLSILOXY-3-BUTYNE;TRIMETHYL((1-METHYL-2-PROPYNYL)OXY)SILANE;MFCD00190215;3-(trimethylsiloxy)-1-butyne;2-(Trimethylsilyloxy)-3-butyne;2-(trimethyl-silyloxy)-but-3-yne;2-Trimethylsilyloxybut-3-yne;SCHEMBL2192426;DTXSID00939109;AKOS015915712;3-(Trimethylsilyloxy)-1-butyne, 97%;[(But-3-yn-2-yl)oxy](trimethyl)silane;AS-80584;2-(4-chlorophenyl)-oxazole-4-carbaldehyde;FT-0690489;Trimethyl[(1-methyl-2-propynyl)oxy]silane #;J-011394

Chemical Property of 3-(Trimethylsilyloxy)-1-butyne

Chemical Property:

• Appearance/Colour: clear pale yellow liquid
• Vapor Pressure: 23.5mmHg at 25°C
• Melting Point: 127-131 °C(lit.)
• Refractive Index: n20/D 1.405(lit.)
• Boiling Point: 114.5 °C at 760 mmHg
• Flash Point: 9.8 °C
• PSA: 9.23000
• Density: 0.835 g/cm³
• LogP: 1.85960
• Storage Temp.: Refrigerator (+4°C)
• Sensitive.: Moisture Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 142.081391600
• Heavy Atom Count: 9
• Complexity: 126

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-(Trimethylsilyloxy)-1-butyne 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,Xi
• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C#C)O[Si](C)(C)C

Technology Process of 3-(Trimethylsilyloxy)-1-butyne

There total 5 articles about 3-(Trimethylsilyloxy)-1-butyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

but-3-yn-2-ol (2028-63-9) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → 3-(trimethylsiloxy)but-1-yne (17869-76-0,100244-12-0,117924-32-0)

Guidance literature:

at 110 ℃; for 12h;

DOI:10.1055/s-1988-27480

Reference yield: 94.0%

chloro-trimethyl-silane (75-77-4) + but-3-yn-2-ol (2028-63-9) → 3-(trimethylsiloxy)but-1-yne (17869-76-0,100244-12-0,117924-32-0)

Guidance literature:

With 1,1,1,3,3,3-hexamethyl-disilazane; Inert atmosphere;

DOI:10.1002/ejoc.200800965

Reference yield: 60.0%

but-3-yn-2-ol (2028-63-9) → 3-(trimethylsiloxy)but-1-yne (17869-76-0,100244-12-0,117924-32-0)

Guidance literature:

With chloro-trimethyl-silane;

upstream raw materials:

chloro-trimethyl-silane

triethyl-(1-methyl-prop-2-ynyloxy)-stannane

but-3-yn-2-ol

1,1,1,3,3,3-hexamethyl-disilazane

Downstream raw materials:

4-trimethylsilyl-3-butyn-2-ol

(1R,4R,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,2,6-trimethyl-1-((E)-3-trimethylsilanyloxy-but-1-enyl)-cyclohexanol

(1S,4R,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,2,6-trimethyl-1-((E)-3-trimethylsilanyloxy-but-1-enyl)-cyclohexanol

1,3,5-tris(1-(trimethylsilyloxy)ethyl)benzene