17874-78-1

Usage

Uses

Used in Pharmaceutical Industry:
6-(Ethoxycarbonyl)nicotinic acid is used as a key intermediate in the production of drugs and other organic compounds. Its unique structure and properties make it an essential component in the synthesis of a wide range of pharmaceuticals, contributing to the development of new and improved medications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-(Ethoxycarbonyl)nicotinic acid is utilized as a valuable reagent for the synthesis of various compounds with potential therapeutic applications. Its unique structure allows for the creation of novel molecules with specific biological activities, furthering the understanding of drug action and the discovery of new therapeutic agents.
Used in Agrochemicals:
6-(Ethoxycarbonyl)nicotinic acid also finds applications in the agrochemical industry, where it serves as a building block for the synthesis of various agrochemicals. Its use in this field contributes to the development of effective and environmentally friendly solutions for agricultural challenges.
Used in Drug Development:
Due to its unique structure and properties, 6-(Ethoxycarbonyl)nicotinic acid has potential applications in drug development. It can be used as a starting material for the synthesis of new drug candidates, facilitating the discovery and development of innovative treatments for various diseases and conditions.

InChI:InChI=1/C9H9NO4/c1-2-14-9(13)7-4-3-6(5-10-7)8(11)12/h3-5H,2H2,1H3,(H,11,12)

Upstream product

• 5552-44-3 ethyl 2,5-pyridinedicarboxylate 
• 100-26-5 Pyridine-2,5-dicarboxylic acid 
• 64-17-5 ethanol 

Downstream Products

• 67515-94-0 5-(3-trifluoromethyl-benzylamino)-pyridine-2-carboxylic acid 
• 67516-46-5 5-(4-Trifluoromethyl-benzylamino)-pyridine-2-carboxylic acid 
• 67516-24-9 5-[1-(4-Fluoro-phenyl)-ethylamino]-pyridine-2-carboxylic acid 
• 67516-31-8 5-(4-tert-Butyl-benzylamino)-pyridine-2-carboxylic acid 
• 67516-25-0 5-(1-Phenyl-ethylamino)-pyridine-2-carboxylic acid 
• 41051-03-0 ethyl 5-cyano-2-pyridinecarboxylate 
• 65346-04-5 5-cyano-2-pyridinecarboxamide 
• 788801-45-6 [tert-butoxycarbonyl-(1-cyclohexylmethyl-2-{2-[(6-methylsulfanylcarbonimidoyl-pyridin-3-ylmethyl)-carbamoyl]-2,5-dihydro-pyrrol-1-yl}-2-oxo-ethyl)-amino]-acetic acid tert-butyl ester 
• 182291-44-7 [tert-butoxycarbonyl-(1-cyclohexylmethyl-2-oxo-2-{2-[(6-thiocarbamoyl-pyridin-3-ylmethyl)-carbamoyl]-2,5-dihydro-pyrrol-1-yl}-ethyl)-amino]-acetic acid tert-butyl ester 
• 182291-43-6 tert-butyl {(tert-butoxycarbonyl)[(1R)-2-[(2S)-2-({[(6-cyano-3-pyridinyl)methyl]amino}carbonyl)-2,5-dihydro-1H-pyrrol-1-yl]-1-(cyclohexylmethyl)-2-oxoethyl]amino}acetate 
• 182159-74-6 ((R)-2-{(S)-2-[(6-Carbamoyl-pyridin-3-ylmethyl)-carbamoyl]-2,5-dihydro-pyrrol-1-yl}-1-cyclohexylmethyl-2-oxo-ethyl)-carbamic acid tert-butyl ester 
• 182291-42-5 ((R)-2-{(S)-2-[(6-Cyano-pyridin-3-ylmethyl)-carbamoyl]-2,5-dihydro-pyrrol-1-yl}-1-cyclohexylmethyl-2-oxo-ethylamino)-acetic acid tert-butyl ester 
• 182159-75-7 ((R)-2-{(S)-2-[(6-Cyano-pyridin-3-ylmethyl)-carbamoyl]-2,5-dihydro-pyrrol-1-yl}-1-cyclohexylmethyl-2-oxo-ethyl)-carbamic acid tert-butyl ester 
• 302341-61-3 tert-bulyl N-[(6-cyanopyridin-3-yl)methyl]carbamate 

Relevant academic research and scientific papers

AMIDE COMPOUNDS

The present invention provides compounds represented by the formula (Ia) the formula (Ib) the formula (Ic) and the formula (Id) wherein each symbol is as defined in the specification. According to the present invention, these compounds have a DGAT inhibit

Technical scale synthesis of a new and highly potent thrombin inhibitor

In this account, we describe the development of an efficient and convergent process for the peptidomimetic thrombin inhibitor 1 on production plant scale. Starting from nicotinonitrile (13), (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxy-2- pyrrolidinecarboxylic acid (5) and (2R)-2-amino-3-cyclohexylpropanoic acid (29) compound 1 was obtained in 16 chemical steps. New methods had been developed for the preparation of the key intermediate dehydroproline 22 and the transformation of nitriles into amidines. The thrombin inhibitor 1 was isolated by special techniques (nanofiltration and spray drying). Almost all salts of 1 are amorphous, however, a crystalline complex was obtained with 1,2-benzisothiazol-3(2H)-one 1,1-dioxide (Saccharin).