17878-43-2

Basic information

• Product Name: Magnesium, bromo[4-(trimethylsilyl)phenyl]-
• CAS NO: 17878-43-2
• Molecular Formula: C9H13BrMgSi
• Molecular Weight: 253.497
• Mol File: 17878-43-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Magnesium, bromo[4-(trimethylsilyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Magnesium, bromo[4-(trimethylsilyl)phenyl]-(17878-43-2)
• EPA Substance Registry System: Magnesium, bromo[4-(trimethylsilyl)phenyl]-(17878-43-2)

Safety Data

• Hazardous Substances Data: 17878-43-2(Hazardous Substances Data)

Upstream product

• 6999-03-7 1-bromo-4-(trimethylsilyl)benzene 
• 60-29-7 diethyl ether 

Downstream Products

• 18751-44-5 [4-(9,10-dihydro-acridin-9-yl)-phenyl]-trimethyl-silane 
• 18042-44-9 4-trimethylsilylpropiophenone 
• 18105-93-6 4-methyl-4'-trimethylsilanyl-benzophenone 
• 18105-99-2 4-methoxy-4'-trimethylsilanyl-benzophenone 
• 17933-83-4 4-(trimethylsilyl)benzophenone 
• 18840-72-7 {(C₆H₅)3SnC₆H₄-p-Si(CH₃)3 
• 18052-57-8 2-(4-trimethylsilanyl-phenyl)-propan-2-ol 
• 174224-35-2 2β-carbomethoxy-3β-(4'-trimethylsilylphenyl)tropane 
• 15290-29-6 4-(trimethylsilyl)benzoic acid 
• 18550-13-5 bis-(4-trimethylsilylphenyl)-phosphorus acid 
• 18848-96-9 tris[(p-trimethylsilyl)phenyl]phosphine 
• 18848-94-7 tris-(4-trimethylsilylphenyl)-phosphinoxide 
• 18055-56-6 bis(4-((trimethyl)silyl)phenyl)phosphine chloride 
• 18764-93-7 (C₆H₅)2Sn{C₆H₄-p-Si(CH₃)3}2 

Relevant articles and documents

Chromium(II)-Catalyzed Diastereoselective and Chemoselective Csp2-Csp3 Cross-Couplings Using Organomagnesium Reagents

A simple protocol for performing chromium-catalyzed highly diastereoselective alkylations of arylmagnesium halides with cyclohexyl iodides at ambient temperature has been developed. Furthermore, this ligand-free CrCl2 enables efficient electrophilic alkenylations of primary, secondary, and tetiary alkylmagnesium halides with readily available alkenyl acetates. Moreover, this chemoselective C-C coupling reaction with stereodefined alkenyl acetates proceeds in a stereoretentive fashion. A wide range of functional groups on alkyl iodides and alkenyl acetates are well tolerated, thus furnishing functionalized Csp2-Csp3 coupling products in good yields and high diastereoselectivity. Detailed mechanistic studies suggest that the in situ generated low-valent chromium(I) species might be the active catalyst for these Csp2-Csp3 cross-couplings.

TETRAHYDROFURANYL SULFONAMIDES FOR USE AS AMPA MODULATORS IN THE TREATMENT OF CNS DISORDERS

The invention is directed to a class of compounds, including the pharmaceutically acceptable salts of the compounds, having the structure of formula (I): as defined in the specification. The invention is also directed to compositions containing the compounds of formula (I). They are useful in the treatment of CNS disorders.