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15290-29-6

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15290-29-6 Usage

General Description

4-(trimethylsilyl)benzoic acid is a chemical compound with the molecular formula C11H14O2Si. It is a derivative of benzoic acid, with a trimethylsilyl group attached to the 4-position of the benzene ring. 4-(trimethylsilyl)benzoic acid is commonly used as a protecting group in organic synthesis, where the trimethylsilyl group can be removed under mild conditions to reveal the free carboxylic acid group. It is also used as a building block in the synthesis of pharmaceuticals and agrochemicals. Additionally, 4-(trimethylsilyl)benzoic acid is a key intermediate in the preparation of a variety of organic compounds and is widely used in research and industrial applications.

Check Digit Verification of cas no

The CAS Registry Mumber 15290-29-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,9 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 15290-29:
(7*1)+(6*5)+(5*2)+(4*9)+(3*0)+(2*2)+(1*9)=96
96 % 10 = 6
So 15290-29-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O2Si/c1-13(2,3)9-6-4-8(5-7-9)10(11)12/h4-7H,1-3H3,(H,11,12)

15290-29-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-trimethylsilylbenzoic acid

1.2 Other means of identification

Product number -
Other names Benzoic acid, 4-(trimethylsilyl)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15290-29-6 SDS

15290-29-6Relevant articles and documents

Direct carboxylation of simple arenes with CO2 through a rhodium-catalyzed C-H bond activation

Suga, Takuya,Mizuno, Hajime,Takaya, Jun,Iwasawa, Nobuharu

supporting information, p. 14360 - 14363 (2015/02/19)

Direct carboxylation of simple arenes under atmospheric pressure of CO2 is achieved through a rhodium-catalyzed C-H bond activation without the assistance of a directing group. Various arenes such as benzene, toluene, xylene, electron-rich or electron-deficient benzene derivatives, and heteroaromatics are directly carboxylated with high TONs. This journal is

SILICON DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS

-

Page/Page column 68, (2009/04/25)

The present invention relates to a novel class of Silicon derivatives. The Silicon compounds can be used to treat cancer. The Silicon compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation,

Model reactions targeted at the synthesis of carbon-14 labeled CI-996, a potent antagonist of angiotensin II receptor (1)

Ekhato,Huang

, p. 213 - 220 (2007/10/02)

A reaction sequence suitable for the preparation of an analog of 2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl-4-[2-(tr ifluoroacetyl)-1H-pyrrol-1-yl]-1H-imidazole-5-carboxylic acid, with 14C at the methylene bridge was developed. The would-be labeled fragment (12) was derived from 4-iodobenzenemethanol (6) which itself was constructed from 1,4-dibromobenzene by the application of silicon chemistry. Pd(o) catalyzed coupling of TBDMS protected 6 and a tetrazole borate 10 gave the compound 12 which upon further transformation to the mesylate 13, N-alkylated an imidazole to furnish target compound.

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