18042-44-9

Upstream product

• 123-62-6 propionic acid anhydride 
• 17878-43-2 [4-(trimethylsilyl)phenyl]magnesium bromide 
• 88-15-3 2-Acetylthiophene 
• 75-77-4 chloro-trimethyl-silane 
• 13183-70-5 1,4-bis-(trimethylsilyl)benzene 
• 79-03-8 propionyl chloride 
• 107134-72-5 [4-(dichloroboryl)phenyl]trimethylsilane 
• 93-55-0 1-phenyl-propan-1-one 
• 56255-86-8 2-(4-Bromo-phenyl)-2-ethyl-[1,3]dioxolane 

Downstream Products

• 1009-43-4 4-(trimethylsilyl)styrene 

Relevant academic research and scientific papers

Mg-promoted reductive coupling of aromatic carbonyl compounds with trimethylsilyl chloride and bis(chlorodimethylsilyl) compounds

Mg-promoted reductive coupling of aromatic carbonyl compounds (1) with chlorosilanes, such as trimethylsilyl chloride (TMSCl:2), 1,2- bis(chlorodimethylsilyl)ethane (3) and 1,5-dichlorohexamethyltrisiloxane (4), in N,N-dimethylformamide (DMF) at room temperature brought about selective and facile reductive formation of both of carbon-silicon and oxygen-silicon bonds to give the corresponding α-trimethylsilylalkyl trimethylsilyl ethers (5) and cyclic siloxanes (6), (7) in moderate to good yields, respectively. The present facile and selective coupling may be initiated through electron transfer from Mg metal to aromatic carbonyl compounds (1).

Synthesis and reaction of secondary and primary diorganozinc reagents using a boron-zinc exchange reaction. A useful method for the stereo- and regioselective formation of new carbon-carbon bonds

Applications of the boron-zinc exchange reaction to make new carbon-carbon bonds are reviewed. Functionalized chiral secondary alkylzinc reagents can be prepared by this exchange reaction and allows to perform formal enantioselective Michael-additions wit

One-pot chemoselective functionalization of arylsilanes via cascade metal-metal exchange reactions

A cascade-transmetallation sequence allows a one-pot conversion of arylsilanes into functionalized arylcoppers; they react with various types of electrophiles (allylic halides, acid chlorides, bromoalkynes); bimetallic zinc-copper-reagents can be prepared by this method either directly or in a sequential fashion.

Mg-promoted reductive cross coupling of carbonyl compounds with trimethylsilyl chloride

Mg-promoted cross-coupling of aromatic carbonyl compounds with trimethylsilyl chloride (TMSCl) in DMF at room temperature brought about reductive carbon-silicon bond formation to give the corresponding α-trimethylsilylalkyl trimethylsilyl ethers selectively in good yields.The reaction may be initiated through electron transfer from Mg metal to the carbonyl compounds.