17878-47-6

Basic information

• Product Name: 1-BROMO-3-TRIMETHYLSILYLBENZENE
• Synonyms: (3-Bromophenyl)trimethylsilane;1-Bromo-3-(trimethylsilyl)benzene 97%;1-BROMO-3-TRIMETHYLSILYLBENZENE
• CAS NO: 17878-47-6
• Molecular Formula: C₉H₁₃BrSi
• Molecular Weight: 229.18902
• Mol File: 17878-47-6.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 50°C/0.5mmHg(lit.)
• Flash Point: 129.2°C
• Appearance: /
• Density: 1.230 g/mL at 25 °C
• Vapor Pressure: 0.0905mmHg at 25°C
• Refractive Index: n20/D1.532
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 1-BROMO-3-TRIMETHYLSILYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-3-TRIMETHYLSILYLBENZENE(17878-47-6)
• EPA Substance Registry System: 1-BROMO-3-TRIMETHYLSILYLBENZENE(17878-47-6)

Safety Data

• Statements: 53
• WGK Germany: 3
• Hazardous Substances Data: 17878-47-6(Hazardous Substances Data)

Usage

General Description

1-Bromo-3-trimethylsilylbenzene is an organosilicon compound that is used as a building block in organic synthesis. It is a derivative of benzene with a bromine atom attached to the 1-position and a trimethylsilyl group attached to the 3-position. 1-BROMO-3-TRIMETHYLSILYLBENZENE is commonly used as a reagent in cross-coupling reactions to form carbon-carbon bonds and in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a precursor in the production of functional materials and polymers. Due to its reactivity and versatility, 1-bromo-3-trimethylsilylbenzene is a valuable compound in the field of organic chemistry and materials science.

InChI:InChI=1/C9H13BrSi/c1-11(2,3)9-6-4-5-8(10)7-9/h4-7H,1-3H3

Upstream product

• 591-18-4 1-Bromo-3-iodobenzene 
• 75-77-4 chloro-trimethyl-silane 
• 109-72-8 n-butyllithium 
• 108-36-1 1,3-dibromobenzene 
• 17878-23-8 3,5-dibromo-1-trimethylsilylbenzene 
• 626-39-1 1,3,5-trisbromobenzene 

Downstream Products

• 17887-54-6 3-(trimethylsilyl)benzaldehyde 
• 132236-18-1 2,2,2-Trifluoro-1-(3-trimethylsilylphenyl)-ethanone 
• 17197-34-1 (CH₃)3SnC₆H₄-m-Si(CH₃)3 
• 177171-16-3 3-(trimethylsilyl)phenylboronic acid 
• 15290-28-5 3-trimethylsilylbenzoic acid 
• 1379761-50-8 C₁₇H₁₈O₃ 
• 22515-29-3 methyl 3-(trimethylsilyl)benzoate 
• 124153-65-7 [3-(3,3-Dimethyl-but-1-ynyl)-phenyl]-trimethyl-silane 
• 19061-38-2 (9s,10s)-9,10-diphenyl-9,10-dihydro-9,10-epoxyanthracene 
• 17881-83-3 3-trimethylsilylbenzenethiol 
• 337535-27-0 3-bromo-3'-methoxy-1,1'-biphenyl 

Relevant articles and documents

Synthesis, radiosynthesis, and biological evaluation of carbon-11 labeled 2β-carbomethoxy-3β-(3′-((Z)-2-haloethenyl)phenyl)nortropanes: Candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography

2β-Carbomethoxy-3β-(3′-((Z)-2-iodoethenyl)phenyl)nortropane (mZIENT, 1) and 2β-carbomethoxy-3β-(3′-((Z)-2-bromoethenyl) phenyl)nortropane (mZBrENT, 2) were synthesized and evaluated for binding to the human serotonin, dopamine, and norepinephrine transpor

Oxidative homocoupling reaction of aryltrimethylsilanes by Pd/o-chloranil catalysis

A practical oxidative homocoupling reaction of aryltri-methylsilanes has been achieved by Pd/o-chloranil catalytic system. The reaction shows the good functional group tolerability toward bromo, fluoro, ester, and methoxy groups to give a series of biaryls bearing electron-withdrawing and -donating groups. The boronate group is also retained on biaryls without any ArB bond cleavage, which is highly advantageous for orthogonal coupling.

cis-Cinnamic acid selective suppressors distinct from auxin inhibitors

The activity of cis-cinnamic acid (cis-CA), one of the allelochemicals, in plants is very similar to that of indole-3-acetic acid (IAA), a natural auxin, and thus cis-CA has long been believed to be an analog of auxin. We have reported some structure-acti