178876-92-1

Basic information

• Product Name: 6-bromo-5-hydroxy-2-pyridinecarboxylic acid
• Synonyms: 6-bromo-5-hydroxy-2-pyridinecarboxylic acid;2-Pyridinecarboxylic acid, 6-broMo-5-hydroxy-;6-Bromo-5-hydroxy-pyridine-2-carboxylic acid
• CAS NO: 178876-92-1
• Molecular Formula: C6H4BrNO3
• Molecular Weight: 218
• Mol File: 178876-92-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 486.9±45.0 °C(Predicted)
• Appearance: /
• Density: 1.985±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.50±0.10(Predicted)
• CAS DataBase Reference: 6-bromo-5-hydroxy-2-pyridinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-bromo-5-hydroxy-2-pyridinecarboxylic acid(178876-92-1)
• EPA Substance Registry System: 6-bromo-5-hydroxy-2-pyridinecarboxylic acid(178876-92-1)

Safety Data

• Hazardous Substances Data: 178876-92-1(Hazardous Substances Data)

Upstream product

• 54232-43-8 6-bromo-5-methoxy-2-pyridinecarboxylic acid 
• 23003-35-2 2-bromo-3-hydroxy-6-methylpyridine 
• 24207-22-5 2-bromo-3-methoxy-6-methyl-pyridine 
• 1121-78-4 5-Hydroxy-2-methylpyridine 
• 170235-18-4 methyl 2-bromo-3-methoxy-6-pyridinecarboxylic acid 

Downstream Products

• 170235-19-5 methyl 2-bromo-3-hydroxy-6-pyridinecarboxylate 
• 170235-18-4 methyl 2-bromo-3-methoxy-6-pyridinecarboxylic acid 

Relevant articles and documents

Total synthesis of dimethyl sulfomycinamate

Dimethyl sulfomycinamate (1), a methanolysis product from the natural antibiotic sulfomycin I, is synthesized in 11 steps. The chemistry of various pyridine, thiazole, and oxazole heterocycles and their coupling reactions under palladium catalysis are examined. The key transformations in the synthesis are the selective palladium-catalyzed coupling reactions on doubly activated pyridine 62 and the condensation reaction between bromo ketone 69 and amide 28 to form the oxazole moiety 76. The first preparation of oxazole triflates is described, as are some of their chemical properties.