17890-34-5

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 100-61-8 N-methylaniline 
• 25561-30-2 N,O-Bis(trimethylsilyl)trifluoroacetamide 

Downstream Products

• 91638-00-5 N_.N'-Dimethyl-N-phenyl-N'-trimethylsilyl-harnstoff 
• 19009-45-1 N-methyl-N-phenylthiocarbamoyl chloride 
• 136490-81-8 S-trimethylsilyl O-i-propyldithiocarbonate 
• 100244-42-6 O-isopropyl N-methyl-N-phenylthiocarbamate 
• 136490-80-7 S-trimethylsilyl O-propyldithiocarbonate 
• 136490-69-2 N-propoxythiocarbonyl-N-methyl aniline 
• 92636-24-3 N,N-Diethyl-3-(methyl-phenyl-amino)-benzamide 
• 136490-84-1 S-trimethylsilyl O-sec-butyldithiocarbonate 
• 136490-72-7 Nsec-butoxythiocarbonyl-N-methyl aniline 
• 75-77-4 chloro-trimethyl-silane 
• 82942-80-1 N,N'-Dimethylsulfinyldianilin 
• 81927-18-6 1,5-Bis(methylphenylamino)tetraschwefeltetranitrid 
• 33603-50-8 N-methyl-N-phenyl-N-(3-phenylprop-1-enyl)amine 
• 100-61-8 N-methylaniline 

Relevant academic research and scientific papers

Deoxofluorination reactions using N,N-disubstituted aminodifluorosulfinium tetrafluoroborate salts

The synthesis of N,N-disubstituted aminodifluorosulfinium tetrafluoroborate salts is reported, and their behavior as deoxofluorinating agent was evaluated. The deoxofluorination reactions were performed using a primary alcohol, a secondary alcohol and a ketone. Results show that subtle modification of the structure of the reagents can noticeably affect the reactivity and the selectivity in deoxofluorination reactions.

Synthetic routes to, transformations of, and rather surprising stabilities of (N-Methyl-N-phenylcarbamoyl)sulfenyl Chloride, ((N-Methyl-N-phenylcarbamoyl) dithio)carbonyl chloride, and related compounds

(Figure presented) The title compound classes, (carbamoyl)sulfenyl chlorides and ((carbamoyl)dithio)carbonyl chlorides, have been implicated previously as unstable, albeit trappable, intermediates in organosulfur chemistry. The presentwork reports for each of these functional groups: (i) several routes to prepare it in the N-methylaniline family; (ii) its direct structural characterization by several spectroscopic techniques; (iii) its rather unexpected stability and its ultimate fatewhen it decomposes; (iv) a series of further chemical transformations that give highly stable derivatives, each in turn subject to thorough characterization. Relevant kinetic and mechanistic experiments were carried out, including some with p-methyl- and 2,6-dimethyl-substituted N-methylanilines. Given that the title compounds can be isolated and are relatively stable, they may find applications in the preparation of thiolyzable and/or photolabile protecting groups for the sulfhydryl function of cysteine and for the development of new protein synthesis and modification reagents

DISUBSTITUTED-AMINODIFLUOROSULFINIUM SALTS, PROCESS FOR PREPARING SAME AND METHOD OF USE AS DEOXOFLUORINATION REAGENTS

The invention relates to disubstituted-aminodifluorosulfinium salts represented by the formula (I). Processes for preparing same and methods of use as deoxofluorinating reagent is also provided.

Palladium catalysed aryl amination reactions in supercritical carbon dioxide

Palladium catalysed C-N bond formation in supercritical carbon dioxide has been accomplished. Carbamic acid formation is avoided in part through the use of an N-silylamine as the coupling partner. Employing a catalyst system of Pd 2dba3 (1 mol%) and 2-dicyclohexylphosphino-2′, 4′,6′-triisopropyl-1,1′-biphenyl (X-Phos) (2 mol%) enabled the catalytic amination of aryl bromides and chlorides with N-silylanilines to be realised in excellent yield. Extension of the methodology to the N-arylation of N-silyldiarylamines, N-silylazoles and N-silylsulfonamides is reported. The Royal Society of Chemistry 2005.

Development of a new class of chiral phosphorus ligands: P-chirogenic diaminophosphine oxides. A unique source of enantioselection in Pd-catalyzed asymmetric construction of quaternary carbons

We have recently developed a new class of chiral phosphorus ligands: P-chirogenic diaminophosphine oxides. These pentavalent phosphorus compounds have been successfully applied to Pd-catalyzed asymmetric construction of tertiary and quaternary carbons. The actual ligand structure was the trivalent phosphorus species 17, which was generated in situ by BSA-induced P(V) to P(III) transformation of 6, the preligand. Detailed mechanistic studies, including asymmetric amplification and initial rate kinetics, revealed that complex 18 [Pd-17 (1:2) complex] was the active catalyst. The important function of the nitrogen atom on the sidearm in the ligands was also clarified. The source of enantioselection in the construction of asymmetric quaternary carbons was the secondary ligand substrate interaction mediated by N-Zn coordination.