17931-26-9

Upstream product

• 2476-69-9 2-Amino-1-thiocyanatonaphthalene 
• 77287-34-4 formamide 
• 91-59-8 naphthalen-2-ylamine 
• 75-15-0 carbon disulfide 
• 53338-20-8 2-aminonaphthalene-1-thiol 
• 67-68-5 dimethyl sulfoxide 
• 90016-93-6 2-Amino-1-iodonaphthalene 
• 612-52-2 2-naphthylamine hydrochloride 
• 1636-33-5 2-naphthyl isothiocyanate 

Downstream Products

• 17931-25-8 2-chloronaphtho<2,1-d>thiazole 
• 14889-08-8 2-hydrazinonaphtho<2,1-d>thiazole 

Relevant academic research and scientific papers

Method for synthesizing thionaphthothiazolone compound under catalysis of copper

The invention discloses a method for synthesizing a thionaphthothiazolone compound under the catalysis of copper. The synthesis method comprises the following steps: adding an N-substituted-2-naphthylamine compound, potassium sulfide, elemental sulfur, a catalyst and dimethyl sulfoxide into a reaction tube, carrying out a stirring reaction at 120-150 DEG C, carryin gout cooling to room temperatureafter the reaction is finished, and carrying out separation and purification on a product to obtain the thionaphthothiazolone compound. According to the reaction, the N-substituted-2-naphthylamine compound is used as a substrate, dimethyl sulfoxide is used for providing a carbon source, potassium sulfide and elemental sulfur are used for providing a sulfur source, and the thionaphthothiazolone compound is synthesized under the catalysis of cuprous iodide. According to the invention, the reaction does not need any additive, the N-substituted-2-naphthylamine is adopted to replace o-halogen N-substituted-2-naphthylamine, and the use of CS2 and a complex sulfur source is avoided, so a direct, green, efficient and valuable approach is developed for the synthesis of thionaphthothiazolone compounds.

A catalyst-free and additive-free method for the synthesis of benzothiazolethiones from: O -iodoanilines, DMSO and potassium sulfide

Under catalyst-free and additive-free conditions, a novel, convenient, eco-friendly method for the synthesis of benzothiazolethiones has been developed. The three-component reaction of o-iodoanilines and K2S with DMSO proceeded smoothly and the corresponding benzothiazolethiones were obtained with good isolated yields. Meanwhile, this method could be used for the synthesis of thioureas from primary diamines. Furthermore, mechanism research showed that DMSO not only functioned as a carbon source, but also as a mild oxidant in this reaction.

SYNTHESIS OF HETEROCYCLES : SYNTHESIS OF NAPHTHO-TRIAZOLOTRIAZEPINES

Some new fluorinated naphthothiazolotriazepines have been synthesized by condensation of 2-hydrazinonaphthothiazoles with 1,3-diketones.