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90016-93-6

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90016-93-6 Usage

General Description

2-AMINO-1-IODONAPHTHALENE, also known as 1-amino-2-iodonaphthalene, is a chemical compound with the molecular formula C10H7IN. It is a derivative of naphthalene and contains an amino group and an iodine atom attached to the naphthalene ring. 2-AMINO-1-IODONAPHTHALENE is primarily used as a precursor in organic synthesis, particularly in the formation of various functionalized naphthalene derivatives. It is also utilized in the production of dyes, pharmaceuticals, and other organic compounds. Additionally, 2-AMINO-1-IODONAPHTHALENE has been investigated for its potential application in organic light-emitting diodes (OLEDs) and other optoelectronic devices. However, it is important to handle this compound with care, as it is considered hazardous due to its toxicity and potential environmental impact.

Check Digit Verification of cas no

The CAS Registry Mumber 90016-93-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,0,1 and 6 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 90016-93:
(7*9)+(6*0)+(5*0)+(4*1)+(3*6)+(2*9)+(1*3)=106
106 % 10 = 6
So 90016-93-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H8IN/c11-10-8-4-2-1-3-7(8)5-6-9(10)12/h1-6H,12H2

90016-93-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-iodonaphthalen-2-amine

1.2 Other means of identification

Product number -
Other names 1-Jod-2-amino-naphthalin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:90016-93-6 SDS

90016-93-6Relevant articles and documents

Enantioselective Construction of Axially Chiral Amino Sulfide Vinyl Arenes by Chiral Sulfide-Catalyzed Electrophilic Carbothiolation of Alkynes

Ji, Jieying,Jiang, Quanbin,Liang, Yaoyu,Luo, Jie,Zhang, Xiaoyan,Zhao, Xiaodan

, p. 4959 - 4964 (2020/02/11)

The enantioselective construction of axially chiral compounds by electrophilic carbothiolation of alkynes is disclosed for the first time. This enantioselective transformation is enabled by the use of a Ts-protected bifunctional sulfide catalyst and Ms-protected ortho-alkynylaryl amines (Ts=tosyl; Ms=mesyl). Both electrophilic arylthiolating and electrophilic trifluoromethylthiolating reagents are suitable for this reaction. The obtained products of axially chiral vinyl–aryl amino sulfides can be easily converted into biaryl amino sulfides, biaryl amino sulfoxides, biaryl amines, vinyl–aryl amines, and other valuable difunctionalized compounds.

EGFR INHIBITORS, COMPOSITIONS AND METHODS THERE OF

-

Page/Page column 58-59, (2020/10/20)

The present invention relates to compounds of Formula I, methods of using the compounds as EGFR inhibitors, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders s

A High-Throughput Assay for Arylamine Halogenation Based on a Peroxidase-Mediated Quinone-Amine Coupling with Applications in the Screening of Enzymatic Halogenations

Hosford, Joseph,Shepherd, Sarah A.,Micklefield, Jason,Wong, Lu Shin

supporting information, p. 16759 - 16763 (2016/02/12)

Arylhalides are important building blocks in many fine chemicals, pharmaceuticals and agrochemicals, and there has been increasing interest in the development of more "green" halogenation methods based on enzyme catalysis. However, the screening and development of new enzymes for biohalogenation has been hampered by a lack of high-throughput screening methods. Described herein is the development of a colorimetric assay for detecting both chemical and enzymatic arylamine halogenation reactions in an aqueous environment. The assay is based on the unique UV/Vis spectrum created by the formation of an ortho-benzoquinone-amine adduct, which is produced by the peroxidase-catalysed benzoquinone generation, followed by Michael addition of either a halogenated or non-halogenated arylamine. This assay is sensitive, rapid and amenable to high-throughput screening platforms. We have also shown this assay to be easily coupled to a flavin-dependent halogenase, which currently lacks any convenient colorimetric assay, in a "one-pot" workflow.

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