18001-14-4

Usage

Molecular Structure

The compound consists of a benzoic acid derivative with a trimethylsiloxy group and a methyl ester group.

Usage

It is often used as a building block in organic synthesis to create various other chemical compounds.

Potential Applications

The compound has a variety of potential applications in fields such as pharmaceuticals, agrochemicals, and materials science.

Unique Value

Its unique structure and reactivity make it a valuable tool for chemists and researchers working in these fields.

Health and Safety Risks

It is important to handle 2-(Trimethylsiloxy)benzoic acid methyl ester with caution as it may pose some health and safety risks if not used properly.

Upstream product

• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 119-36-8 methyl salicylate 
• 1825-62-3 ethyl trimethylsilyl ether 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 17763-70-1 methyl 2-(trifluoromethylsulfonyloxy)benzoate 
• 119-36-8 methyl salicylate 
• 420-56-4 trimethylsilyl fluoride 

Relevant academic research and scientific papers

Preparation of nano silica supported sodium hydrogen sulfate: As an efficient catalyst for the trimethyl, triethyl and t-butyldimethyl silylations of aliphatic and aromatic alcohols in solution and under solvent-free conditions

Nano silica supported sodium hydrogen sulfate has been prepared by mixing NaHSO4 with activated Nano silicagel. We wish to report a new method for the synthesis of trimethyl (TMS), triethyl (TES) and t-butyldimethyl silyl (TBS) ethers from benzylic, allylic, propargylic alcohols, phenols, naphtholes and some of phenolic drugs in the solution and under solvent-free conditions.

A mild and highly efficient method for the preparation of silyl ethers using Fe(HSO4)3/Et3N by chlorosilanes

Avery efficient and mild procedure for preparation of silyl ethers from benzylic, allylic, propargilic alcohols, phenols, naphtoles and some of phenolic drugs with trimethylsilylchloride (TMSCl), triethylsilylchloride (TESCl) and t-buthyldimethylsilyl chloride (TDSCl) ethers in the presence of Fe(HSO 4)3/Et3N in roomtemperature in excellent yields is reported. This procedure also allows the excellent selectivity for silylation of alcohols and phenols.

Silylation of hydroxy groups with HMDS under microwave irradiation and solvent-free conditions

Phenols and alcohols are silylated with hexamethyldisilazane (HMDS) under microwave irradiation in solvent-free condition in good to excellent yields.