1802-38-6

Upstream product

• 46449-60-9 bis(4-chloro-phenyl)-iodonium cation 
• 29025-67-0 1-(4-chlorophenyl)silatrane 
• 86822-36-8 [(C₅H₅)2Ti(C₆H₄Cl)(CH₃)] 
• 1600-27-7 mercury(II) diacetate 
• 108-90-7 chlorobenzene 
• 7647-14-5 sodium chloride 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 16507-96-3 p-chlorophenyl-triethyltin 
• 7277-07-8 4-ClC₆H₄SbCl₂ 

Downstream Products

• 2050-68-2 4,4'-dichlorobiphenyl 
• 90-98-2 4,4'-Dichlorobenzophenone 
• 7497-60-1 (4-Chlorophenyl)(4-nitrophenyl)methanone 
• 4250-46-8 dichloro-(4-chloro-phenyl)-borane 
• 15799-48-1 tetra(p-chlorophenyl)tin 
• 180194-92-7 [(CH₃C₉H₅NOCH₂C₂N₂OS)HgC₆H₄Cl] 
• 180194-95-0 [(CH₃C₂N₂SS)HgC₆H₄Cl] 

Relevant academic research and scientific papers

Synthesis, characterization and applications of organomecury(II) pyrrolidine-N-thiohydrazide complexes

The complexes of organomercury(II) with pyrrolidine-N-thiohydrazide of the type RHg(L)Cl where[R=C6H5(phenyl), p-ClC6H4(p-chlorophenyl), p-BrC6H4(p-bromophenyl), o-, p-HOC6H4, (o-,p-hydroxyphenyl), L = pyrrolidine-N-thiohydrazide, have been synthesized and characterized by elemental analysis, IR,1H-NMR and electronic spectral analysis. Thermogravimetric and differential thermal analytical curves are used to calculate thermodynamic parameters and variations in these parameters have been correlated with complex structural parameters. All complexes were tested in vitro for their antibacterial activity against Gram-negative bacteria, namely, Escherichia coli, Zymomonas mobilis and against two pathogenic fungal strains, namely, Aspergillus niger and Cerveleria.

Microwave induced novel synthetic route to organomercurials

Organomercurials of 2-mercapto-5-methyl-1,3,4-thiadiazole and 2-mercapto-5-[4′-methyl quinolinyl-2-oxy methyl]-1,3,4-oxadiazole with aryl mercuric chloride have been synthesized under microwave irradiation in open vessels in a domestic microwave oven within a few minutes. This reaction rate was ca 100 times faster than the reaction rate in the conventional way. These Organomercurials have a 1:1 stoichiometric ratio of aryl mercury and thiadiazole or oxadiazole moiety. Copyright

Substituent effects in aromatic substitution of aryltriethyltin compounds by mercuric halides

Second-order rate constants are reported for the reaction of some YC6H4SnEt3 compounds with mercuric halides in tetrahydrofuran, and show that the reaction is one of low selectivity.The substituent effects can be correlated only in terms of Hammett ?-constants, and the data for the meta-methoxy group are anomalous.The results indicate that the rate determining step involves reaction of a ?-complex.Activation parameters are reported, and are in accordance with the suggested mechanism.

DIRECT TRANSFER OF ALIPHATIC AND AROMATIC SUBSTITUENTS FROM ORGANOSILATRANES TO MERCURY(II) SPECIES

The relative reaction rates of several silatranes (derivatives of 2,8,9-trioxa-5-aza-1-silatricyclo1,5>undecane) and HgCl2 in acetone-d6 to yield the corresponding organomercury compound are of the order of e.g., 5 * 10-1 1 mol-1 sec-1 or slightly less, a rate that is unexpectedly high compared to the essentially inert parent organotrialkoxysilanes.Thus, the apical Si-C bond of the silatrane is extraordinarily susceptible to direct electrophilic attack by mercury(II).The rates decrease in the order CH2=CH, C6H5, p-ClC6H4 > CH3 > CH3CH2, CH3CH2CH2 > C6H11, ClCH2, Cl2CH, CH3CH2O.The effects of varying the solvent and the counterions are noted, and the probable mechanism is discussed.

REARRANGEMENT AND CATALYSIS IN THE SEYFERTH REACTION.

The Seyferth reagent PhHgCBr//3 reacts with trans-1,2-dichloroethene to give two major products, trans-1,1-dibromo-2,3-dichlorocyclopropane (C) and 1,1-dibromo-3,3-dichloropropene (P). The stereospecifically formed cyclopropane is consonant with a singlet carbene mechanism, but the rearranged propene requires a second intermediate. Observation that the concentration ratio left bracket P right bracket / left bracket C right bracket is inversely proportional to the concentration of the alkene demonstrates that there are two intermediates, that the cyclopropane comes from the first-formed intermediate, and that the propene comes from the second-formed intermediate.

Selectivity and reactivity in reactions of methylaryltitanium(IV) complexes with electrophiles

Methyl or phenyl for halogen-exchange reactions occur between [TiMe2(η-C5H5)2] or [TiPh2(η-C5H5)2] with [TiX2(η-C5H5)2], X = halogen, to give [TiXMe(η-C5H5)2] or [TiXPh(η-C5H5)2], respectively. The reactions are complicated by parallel decomposition of the methyl- or phenyltitanium complexes, which is catalyzed by [TiX2(η-C5H5)2] or [TiXR(η-C5H5)2]. In general, there is little difference in the rates of reaction of [TiMe2(η-C5H5)2] and [TiPh2(η-C5H5)2] toward the symmetrization reactions. These reagents also transfer a methyl group or phenyl group to platinum(II) or gold(III), but there are again side reactions. The complex [TiMePh(η-C5H5)2] reacts with electrophiles HCl, HOAc, HgCl2, and MeHgCl to give cleavage of both methyl- and phenyltitanium bonds with little selectivity. In cleavage of [TiMe(C6H4X)(η-C5H5) 2] there is a correlation of the selectivity for cleavage of the aryl group by electrophiles HCl or HgCl2 with the σ+ parameters of substituents X. A mechanism of reaction involving electron transfer from the complex to the electrophile followed by rapid cleavage is tentatively suggested.