18042-62-1 Usage
Uses
Used in Organic Synthesis:
N-(TRIMETHYLSILYLMETHYL)PHTHALIMIDE is used as a reagent for the preparation of amide and imide compounds, due to its unique chemical properties and reactivity that facilitate the formation of these compounds.
Used in Protecting Groups:
In the context of protecting groups, N-(TRIMETHYLSILYLMETHYL)PHTHALIMIDE is used to shield functional groups during organic synthesis, allowing for selective reactions to occur at other sites within a molecule.
Used as a Precursor:
N-(TRIMETHYLSILYLMETHYL)PHTHALIMIDE serves as a precursor for various organic transformations, enabling the synthesis of a wide range of complex organic molecules through its versatile reactivity.
Used in Pharmaceutical Industry:
N-(TRIMETHYLSILYLMETHYL)PHTHALIMIDE is used as a key intermediate in the synthesis of pharmaceutical compounds, contributing to the development of new drugs and therapeutic agents.
Used in Chemical Research:
In the field of chemical research, N-(TRIMETHYLSILYLMETHYL)PHTHALIMIDE is employed as a model compound to study reaction mechanisms and explore new synthetic methodologies, further advancing the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 18042-62-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,0,4 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 18042-62:
(7*1)+(6*8)+(5*0)+(4*4)+(3*2)+(2*6)+(1*2)=91
91 % 10 = 1
So 18042-62-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO2Si/c1-16(2,3)8-13-11(14)9-6-4-5-7-10(9)12(13)15/h4-7H,8H2,1-3H3
18042-62-1Relevant academic research and scientific papers
Metal-Free Aminomethylation of Aromatic Sulfones Promoted by Eosin Y
Thierry, Thibault,Pfund, Emmanuel,Lequeux, Thierry
supporting information, p. 14826 - 14830 (2021/10/01)
A metal-free α-aminomethylation of heteroaryls promoted by eosin Y under green light irradiation is reported. A large variety of α-trimethylsilylamines as precursor of α-aminomethyl radical species were engaged to functionalize sulfonyl-heteroaryls following a Homolytic Aromatic Substitution (HAS) pathway. This method has provided a range of α-aminoheteroaryl compounds including a functionalized natural product. The mechanism of this late-stage functionalization of aryls was investigated and suggests the formation of a sulfonyl radical intermediate over a reductive quenching cycle.
