180465-66-1

Usage

Uses

Given the lack of specific information about the compound's properties and applications, it is not possible to list its uses in various industries. However, once the compound's characteristics and potential applications are identified through further research and testing, its uses can be categorized and described as follows:
Used in [Application Industry]:
C₂₈H₃₇N₃O₆S is used as [application type] for [application reason].
For example, if the compound were found to have pharmaceutical properties, it could be described as:
Used in Pharmaceutical Industry:
C₂₈H₃₇N₃O₆S is used as a pharmaceutical agent for [specific medical condition or treatment purpose].
Similarly, if the compound were found to have industrial applications, it could be described as:
Used in Chemical Industry:
C₂₈H₃₇N₃O₆S is used as a chemical intermediate for [specific industrial process or product].

Upstream product

• 47173-80-8 N-Boc-D-serine(Bzl)-OH 
• 178261-41-1 1-(methylsulfonyl)spiro[indoline-3,4’-piperidine] 
• 159634-86-3 1-Methanesulfonyl-spiro[indoline-3,4'-piperidine] hydrochloride 
• 100-39-0 benzyl bromide 
• 100-63-0 phenylhydrazine 
• 122860-33-7 benzyl 4-(hydroxymethyl)piperidine-N-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 6457-49-4 4-piperidinemethanol 
• 184289-84-7 benzyl 1-(methylsulfonyl)spiro[indoline-3,4’-piperidine]-1‘-carboxylate 
• 167484-18-6 benzyl spiro[indoline-3,4’-piperidine]-1‘-carboxylate 
• 184289-85-8 benzyl spiro[indole-3,4'-piperidine]-1'-carboxylate 
• 10314-99-5 benzyl 4-(chlorocarbonyl)piperidine-1-carboxylate 
• 138163-08-3 N-(benzyloxycarbonyl)piperidine-4-carboxaldehyde 
• 10314-98-4 1-benzyloxycarbonylpiperidine-4-carboxylic acid 

Downstream Products

• 159634-87-4 N-[(R)-[(1,2-Dihydro-1-methanesulfonylspiro[3H-indole-3,4'-piperidin]-1'-yl)carbonyl]-2-(phenylmethyloxy)ethyl]-2-[(1,1-dimethyl-ethoxy)carbonyl]amino-2-methyl-propanamide 
• 191487-52-2 MK-677 
• 159634-47-6 Ibutamoren 
• 180465-67-2 C₂₃H₂₉N₃O₄S 

Relevant academic research and scientific papers

A facile synthesis of the spiroindoline-based growth hormone secretagogue, MK-677

A facile and improved route for the synthesis of the orally active spiroindoline-based growth hormone secretagogue, MK-677 was described. The key step adopted the Fischer indole/reduction strategy. The preparation of the key intermediates N-protected piperidine carboxaldehyde 5 and the N-Boc-O-benzyl-d-serine (2) are also optimized.

SULFONAMIDES AND USES THEREOF

Compounds of formulas (I), (II), (III), and (IV) and methods of treating disorders by administering a compound of formula (I), (II), (III), or (IV) are described herein. Examples of disorders include neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders.

THERAPEUTIC COMPOUNDS AND USES THEREOF

Compounds of formula (I) are described herein The compounds can be used, for example, to modulate growth hormone secretagogue receptor (GHS-R). In some instances, the compounds can be used to treat obesity.

Serine derived NK1 antagonists 1: The effect of modifications to the serine substituents

A series of novel serine derived NK1 antagonists is described. The effect of variations in the N-benzyl, O-benzyl and serine groups are used to define the elements which are necessary for binding.

Synthesis of the orally active spiroindoline-based Growth Hormone Secretagogue, MK-677

The preparation of the Merck Growth Hormone Secretagogue; MK-677 is described. A Fischer indole/reduction based strategy provides the novel spiroindoline nucleus of this potent compound. This optimized sequence necessitates the isolation of only one intermediate 10 and provides MK-677 in 48% overall yield from isonipecotic acid 3.