18052-49-8

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 698-87-3 3-phenyl-2-propanol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 54380-53-9 cyclohexa-2,5-dien-1-yl(trimethyl)silane 
• 754-05-2 ethenyltrimethylsilane 

Downstream Products

• 698-87-3 3-phenyl-2-propanol 
• 103-79-7 1-phenyl-acetone 
• 2344-57-2 (β-Phenyl-isopropyl)-(3-phenyl-propyl)-aether 
• 101430-90-4 [2-(benzyloxy)propyl]benzene 
• 2114-33-2 1-phenylpropan-2-yl acetate 

Relevant academic research and scientific papers

Silylation and tetrahydropyranylation of alcohols catalyzed by Al(HSO 4)3

Trimethylsilylation and tetrahydropyranylation of alcohols are efficiently catalyzed by Al(HSO4)3. All reactions were performed under mild and completely heterogeneous conditions in good-to-high yields.

Salt-free preparation of trimethylsilyl ethers by B(C6F 5)3-catalyzed transfer silylation by using a Me 3SiH surrogate

An unprecedented transfer silylation of alcohols catalyzed by the strong Lewis acid B(C6F5)3 is described. Gaseous Me3SiH is released in situ by B(C6F5) 3-catalyzed decomposition of 3-trimethylsilylcyclohexa-1,4-diene and subsequently reacts with an alcohol in a dehydrogenative Si-O coupling promoted by the same boron catalyst. Benzene and dihydrogen are formed during the reaction, but no salt waste is. This expedient protocol is applicable to several silicon groups, and the preparation of trimethylsilyl ethers presented here is potentially useful for alcohol derivatization prior to GLC analysis. Copyright

Cross-linked poly(4-vinylpyridine/styrene) copolymer-supported bismuth(III) triflate: An efficient heterogeneous catalyst for silylation of alcohols and phenols with HMDS

Cross-linked poly(4-vinylpyridine/styrene) copolymer-supported bismuth(III) triflate (30P/S-Bi) effectively activates hexamethyldisilazane (HMDS) for the silylation of alcohols and phenols. By the use of this heterogeneous catalytic system, a wide range of alcohols as well as phenols are converted into their corresponding trimethylsilyl ethers in high yield under mild reaction conditions. The catalyst was reused more than 10 times without significant loss of its catalytic activity.

Silica triflate as a new, efficient, and reusable reagent for the chemoselective silylation of alcohols and phenols and deprotection of silyl ethers

Silica triflate was easily prepared via reaction of silica gel and trifluoromethane sulfonyl chloride at room temperature. This compound can be employed as an efficient and reusable reagent for the chemoselective silylation of alcohols and phenols in solution and under solvent-free conditions. This reagent also effectively catalyzed the deprotection of silyl ethers in refluxing methanol.

Fe(HSO4)3 promoted trimethylsilylation of alcohols and phenols in solution and under solvent-free conditions

Alcohols and phenols are efficiently converted to their corresponding trimethylsilyl ethers with hexamethyldisilazane (HMDS) in the presence of Fe(HSO4)3 in solution and under solvent-free conditions.

SURFACE MODIFIED ORGANIC·INORGANIC HYBRID GLASS, PROTECTING GROUP INDUCED ALCOHOL OR ITS DERIVATIVE AND PRODUCING METHOD THEREOF

Disclosed are a protected alcohol or derivative thereof, a surface- modified organic-inorganic hybrid glass, and preparation methods thereof. More specifically, disclosed are a protected alcohol or derivative thereof and a surface-modified organic-inorganic hybrid glass, which are prepared by allowing a silane compound, having vinyl or a vinyl derivative, to react with an alcohol or derivative thereof or with an organic-inorganic hybrid glass, in the presence of an acid catalyst, a transition metal catalyst and an organic solvent, so as to introduce an organic group thereto even at room temperature, as well as preparation methods thereof. The disclosed invention allows a functional group to be effectively introduced into alcohol or a derivative thereof or into an organic-inorganic hybrid glass, not only high temperatures but also room temperature, and thus is highly effective in introducing compounds having a thermally sensitive functional group, for example, natural compounds or proteins. Also, the invention makes it possible to introduce various organic groups and to separate and purify organic macromolecule-bonded organosilane compounds using a silica gel column so as to effectively introduce large organic functional groups to inorganic materials. Accordingly, the invention is highly useful in the chemical industry.

Trimethylsilylation of alcohols and phenols using KBr as an efficient and reusable catalyst

KBr acts as an efficient and reusable catalyst for the selective and efficient trimethylsilylation of benzylic, primary and secondary aliphatic alcohols and phenols with hexamethyldisilazane. All reactions were performed at room temperature under mild and

Efficient trimethylsilylation and tetrahydropyranylation of alcohols in the presence of 1,3-dibromo-5,5-dimethylhydantoin

Chemoselective trimethylsilylation and tetrahydropyranylation of benzylic and primary and secondary aliphatic alcohols proceed efficiently in the presence of 1,3-dibromo-5,5-dimethylhydantoin (DBH) under mild and completely heterogeneous reaction conditio

A mild and efficient method for chemoselective silylation of alcohols using hexamethyldisilazane in the presence of silica chloride

Reaction of alcohols with hexamethyldisilazane in the presence of silica chloride provides efficiently the corresponding trimethylsilyl ethers. This system discriminates absolutely amines and thiols from alcohols.