180797-81-3

Upstream product

• 228411-87-8 (2E)-11-(tert-butyldimethylsilyloxy)-2-undecen-5-yn-1-ol 
• 228411-90-3 1-benzoyloxy-11-tert-butyldimethylsilyloxy-2,5-undecadiyne 
• 228411-88-9 (2S,3S)-11-(tert-butyldimethylsilyloxy)-2,3-epoxy-5-undecyn-1-ol 
• 180797-76-6 (2S,3S)-1,11-dihydroxy-2,3-epoxy-5-undecyne 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 119837-81-9 tert-butyl(hept-6-yn-1-yloxy)dimethylsilane 
• 56909-02-5 methyl hept-6-ynoate 
• 30964-00-2 hept-6-ynoic acid 
• 2067-33-6 5-bromopentanoic acid 
• 63478-76-2 1-hydroxy-6-heptyne 
• 180797-80-2 (2S,3S)-1,11-bis-tert-butyldiphenylsilyloxy-2,3-epoxy-5-undecyne 

Downstream Products

• 180797-82-4 (2R,3S)-11-tert-butyldiphenylsilyloxy-2,3-epoxy-5-undecyn-1-al 

Relevant academic research and scientific papers

The total synthesis of 20-hydroxyhepoxilins A3, new metabolites of the hepoxilin family of eicosanoids

An enantiodirected total synthesis of 20-hydroxyhepoxilins A3, new eicosanoids of the lipoxygenase metabolism of arachidonic acid, was perfomed. The synthetic samples were found to be identical to the major metabolite formed upon incubation of (85)-hepoxilin A3 with human neutrophiles, which demonstrated that it has the structure of (8S)-20-hydroxy-HxA3.