56909-02-5

Usage

Uses

Used in Chemical Synthesis:
6-Heptynoic acid methyl ester is used as an intermediate in the synthesis of Methyl Stearidonate (M328150), a compound with potential applications in various industries.
Used in Pharmaceutical Industry:
6-Heptynoic acid methyl ester, through its role in synthesizing Methyl Stearidonate, is indirectly involved in the development of compounds with antibacterial properties. Methyl Stearidonate has demonstrated antibacterial activity against various strains of bacteria, including Staphylococcus aureus, S. epidermidis, Salmonella typhimurium, and Proteus vulgaris, making it a valuable compound for pharmaceutical applications.

Upstream product

• 67-56-1 methanol 
• 15295-69-9 hept-6-ynenitrile 
• 928-90-5 5-hexyl-1-ol 
• 75-77-4 chloro-trimethyl-silane 
• 30964-00-2 hept-6-ynoic acid 
• 74-88-4 methyl iodide 
• 2468-56-6 1-iodo-5-hexyne 
• 79496-61-0 hex-5-ynyl methanesulphonate 
• 108545-35-3 8-(2-Nitro-phenylselanyl)-octanoic acid methyl ester 
• 26825-92-3 methyl 8-bromooctanoate 
• 17696-11-6 8-bromooctanoic acid 
• 629-41-4 1,8-Octanediol 
• 2067-33-6 5-bromopentanoic acid 
• 43001-25-8 4-iodobut-1-yne 

Downstream Products

• 228411-90-3 1-benzoyloxy-11-tert-butyldimethylsilyloxy-2,5-undecadiyne 
• 180797-82-4 (2R,3S)-11-tert-butyldiphenylsilyloxy-2,3-epoxy-5-undecyn-1-al 
• 180797-81-3 (2S,3S)-11-tert-butyldiphenylsilyloxy-2,3-epoxy-5-undecyn-1-ol 
• 180797-80-2 (2S,3S)-1,11-bis-tert-butyldiphenylsilyloxy-2,3-epoxy-5-undecyne 
• 82132-58-9 2,3-diphenyl-5,6,7,8-tetrahydroquinoline 
• 130905-56-5 5,6-diphenyl-3-(5-hexynyl)-1,2,4-triazine 
• 106027-21-8 tert-butyl(hept-6-yn-1-yloxy)diphenylsilane 

Relevant academic research and scientific papers

Nickel-Catalyzed Highly Regioselective Hydrocyanation of Terminal Alkynes with Zn(CN)2 Using Water as the Hydrogen Source

The first efficient and general nickel-catalyzed hydrocyanation of terminal alkynes with Zn(CN)2 in the presence of water has been developed. The reaction provides a regioselective protocol for the synthesis of functionalized vinyl nitriles with a range of structural diversity under mild reaction conditions while obviating use of the volatile and hazardous reagent of HCN. Deuterium-labeling experiments confirmed the role of water as the hydrogen source in this hydrocyanation reaction.

PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF

Provided herein are compounds of Formula (I) and compositions useful in increasing PPARS activity. The compounds and compositions provided herein are useful for the treatment of PPARS related diseases (e.g., muscular diseases, vascular disease, demyelinat

Tunable BODIPY derivatives amenable to 'click' and peptide chemistry

Novel azido- and amino-functionalised fluorescent probes based on the BODIPY framework have been developed. The probes can be easily and cheaply synthesised, exhibit the highly desirable BODIPY fluorescent properties, and are amenable to 'click' and pepti

Studies toward the total synthesis of eletefine: An efficient construction of the AB ring system

Synthetic studies toward eletefine, a novel stephaoxocane alkaloid, were undertaken in an attempt to provide a general methodology to aid in the synthesis of other novel stephaoxocanes. An efficient construction of the AB ring system with increased functionality is described which presents a flexible approach to synthesizing the C and D rings of eletefine.

A large scale and concise synthesis of γ-linolenic acid from 4- chlorobut-2-yn-1-ol

A large scale and concise synthesis of γ-linolenic acid is described. The key step of the synthesis involves a copper salt mediated cross-coupling of two different alkynes and chlorobutynol.

The total synthesis of 20-hydroxyhepoxilins A3, new metabolites of the hepoxilin family of eicosanoids

An enantiodirected total synthesis of 20-hydroxyhepoxilins A3, new eicosanoids of the lipoxygenase metabolism of arachidonic acid, was perfomed. The synthetic samples were found to be identical to the major metabolite formed upon incubation of (85)-hepoxilin A3 with human neutrophiles, which demonstrated that it has the structure of (8S)-20-hydroxy-HxA3.

Indirect electroreductive sequential radical reaction catalyzed by a Ni(II) complex. One-step preparation of functionalized (methylene)cyclopentanes

Substituted (methylene)cyclopentanes were prepared by one-step reaction at room temperature from butynyl iodides and activated olefins by sequencing of free radical addition and cyclization reactions. The reactions, which were conducted by indirect electroreduction catalyzed by a nickel(II) complex, proceeded with modest selectivity for formation of the Z(methylene)cyclopentanes.

Intramolecular Diels-Alder Reactions of 1,2,4-Triazines. Synthesis of 2,3-Cyclopentenopyridines and 5,6,7,8-Tetrahydroquinolines

2,3-Cyclopentenopyridines and 5,6,7,8-tetrahydroquinolines are prepared by intramolecular Diels-Alder reactions of appropriately substituted 1,2,4-triazines.Two general routes to the requisite triazine precursors are described.

Acides gras marques en position ω par un nucleide radioactif emetteur γ

The synthesis of many saturated, acetylenic, olefinic (Z or E) fatty acids labeled with 123I or 131I at the ω-position has been achieved.The radioactive iodine atom is introduced by a I-, *I- exchange reaction; the influence on the yield of several parameters - presence of iodine carrier, fatty acid and water concentrations, solution acidity - has been studied.Experimental conditions which produce labeling yields higher than 95percent have been defined; these results have lead to a very easy labeling method used in several hospitals in the external study of myocardial metabolism of fatty acids.