1809-57-0

Basic information

• Product Name: 4-PIPERIDINO-3-BUTEN-2-ONE
• Synonyms: 4-PIPERIDINO-3-BUTEN-2-ONE;3-Buten-2-one, 4-(1-piperidinyl)-
• CAS NO: 1809-57-0
• Molecular Formula: C₉H₁₅NO
• Molecular Weight: 153.2215
• Mol File: 1809-57-0.mol

Chemical Properties

• Boiling Point: 160-162 °C(Press: 16 Torr)
• Appearance: /
• Density: 1.0211 g/cm3
• PKA: 7.10±0.20(Predicted)
• CAS DataBase Reference: 4-PIPERIDINO-3-BUTEN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PIPERIDINO-3-BUTEN-2-ONE(1809-57-0)
• EPA Substance Registry System: 4-PIPERIDINO-3-BUTEN-2-ONE(1809-57-0)

Safety Data

• Hazardous Substances Data: 1809-57-0(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 4643-20-3 (E)-4-chloro-3-buten-2-one 
• 86556-85-6 (E)-4-Oxo-pent-2-enenitrile 
• 5436-21-5 acetylacetaldehyde dimethyl acetal 
• 23074-57-9 4-ethoxybut-3-en-2-one 
• 78-94-4 methyl vinyl ketone 
• 41125-09-1 3-oxo-butyraldehyde; sodium enolate 
• 51731-17-0 trans-4-methoxy-3-buten-2-one 
• 6091-44-7 piperidine hydrochloride 
• 59339-44-5 (E)-4-(benzotriazol-1-yl)-3-butene-2-ne 
• 31172-37-9 trans-4-methoxybut-3-en-2-one 
• 88726-07-2 (E)-3-(p-tolylsulphonyl)but-3-en-2-one 

Downstream Products

• 1367352-53-1 C₁₈H₃₀N₂O 
• 5765-44-6 5-methylisoxazole 
• 87005-15-0 α-bromoacetoacetaldehyde 
• 88860-90-6 1-phenyl-3,4-diacetylpyrazole 

Relevant articles and documents

Methyl β-(benzotriazol-1-yl)vinyl ketone: A new β-acetylvinyl cation equivalent

A simple and efficient two-step approach to methyl β-(benzotriazol-1-yl)vinyl ketone 7 is described. The synthetic utility of compound 7 has been demonstrated by nucleophilic substitutions of the benzotriazolyl group with a range of nucleophiles. Thus, me

A Method for the Preparation of β-Amino-α,β-unsaturated Carbonyl Compounds: Study of Solvent Effect and Mechanism

An efficient method for the preparation of β-amino-α,β-unsaturated carbonyl compounds is demonstrated. Bench-stable sodium 3-oxo-enolates were prepared from carbonyl compounds, and reacted with amines in the presence of an acid and a desiccant. DFT studie

Supported Gold Nanoparticles for Efficient α-Oxygenation of Secondary and Tertiary Amines into Amides

Although the α-oxygenation of amines is a highly attractive method for the synthesis of amides, efficient catalysts suited to a wide range of secondary and tertiary alkyl amines using O2as the terminal oxidant have no precedent. This report describes a novel, green α-oxygenation of a wide range of linear and cyclic secondary and tertiary amines mediated by gold nanoparticles supported on alumina (Au/Al2O3). The observed catalysis was truly heterogeneous, and the catalyst could be reused. The present α-oxygenation utilizes O2as the terminal oxidant and water as the oxygen atom source of amides. The method generates water as the only theoretical by-product, which highlights the environmentally benign nature of the present reaction. Additionally, the present α-oxygenation provides a convenient method for the synthesis of18O-labeled amides using H218O as the oxygen source.

Scalable synthesis of highly reactive 1,3-diamino dienes from vinamidinium salts and their use in Diels-Alder reactions

A practical and chromatography-free synthesis of vinamidinium salts and their use as diene precursors in Diels-Alder reactions is reported. Additionally, 1,3-dipyrrolidino-1,3-butadiene was shown to be significantly more reactive than Rawal's diene in a c

Regio- and Stereo-selective Synthesis of β-Sulphonyl-α,β-Unsaturated Carbonyl Compounds via an Iodosulphonylation-Dehydroiodination Raction

α,β-Unsaturated carbonyl compounds underwent regiospecific iodosulphonylation with toluene-p-sulphonyl iodide or sodium toluene-p-sulphinate and iodine to afford products (2), which were stereoselectively dehydroiodinated by triethylamine to give β-sulphonyl derivatives (3).The reactivity of compounds (3) as cationic β-acylvinyl equivalents, tested with amines or thiophenol, gave compounds (4) resulting from a displacement reaction.

Protonation and Acylation Reactions of Acyclic Enamino Ketones

α,β-Unsaturated β-dialkylamino ketones 4 are converted by means of tetrafluoroboric acid into thermodynamically stable Cα-protonated iminium salts 5. β-(Dialkylamino)vinyl ketones are shown to exist preferentially in the E-s-cis and E-s-trans c

REACTION OF 1-ETHOXY-1-BUTEN-3-ONE WITH AMINES

In the reaction of 1-ethoxy-1-buten-3-one with ammonia and primary and secondary amines the alkoxy group is substituted by an amino group.In the reaction with ammonia 1-amino-1-buten-3-one condenses with the formation of 2-methyl-5-acetylpyridine.

SYNTHESIS OF DERIVATIVES OF 3-OXOBUTANAL CONTAINING FUNCTIONAL GROUPS IN THE MESOMETHYLENE UNIT

The synthesis of 2-bromo-3-oxobutanal was realized by the bromination of 1-dialkylamino-1-buten-3-ones.The trans-enol form predominates in solutions.The direct nitration of 1,1-diethoxy-3-butanol leads to 2-nitro-3-oxobutanal.