87005-15-0

Upstream product

• 767-04-4 1-(1,3-dioxolan-2-yl)propan-2-one 
• 5436-21-5 acetylacetaldehyde dimethyl acetal 
• 67-64-1 acetone 
• 109-94-4 formic acid ethyl ester 
• 1809-57-0 4-piperidin-1-yl-but-3-en-2-one 
• 1190-91-6 4-dimethylamino-3-buten-2-one 
• 1809-59-2 1-diethylamino-1-buten-3-one 
• 19352-94-4 (E)-4-Pyrrolidin-1-yl-but-3-en-2-one 
• 41125-09-1 3-oxo-butyraldehyde; sodium enolate 
• 75-07-0 acetaldehyde 

Downstream Products

• 91516-28-8 1-(thiazol-5-yl) ethan-1-one 
• 10045-50-8 1-(2-phenylthiazol-5-yl)ethan-1-one 
• 87005-17-2 5-acetyl-2-amino-oxazole 
• 5844-71-3 3-bromo-4,4-dimethoxybutan-2-one 
• 598-31-2 1-bromoacetone 
• 856635-57-9 benzimidazolium bromide 
• 53159-71-0 1-(2-aminothiazol-5-yl)ethanone 
• 88158-39-8 2-Amino-5-acetylthiazole Hydrobromide 

Relevant academic research and scientific papers

A novel benzoyl amide compounds

The invention relates to the field of medicinal chemistry, in particular to a novel benzamides compound or a salt acceptable in parmacy of the novel benzamides compound, a preparation method of the novel benzamides compound, a pharmaceutical composition containing the novel benzamides compound and an application of the pharmaceutical composition in preparation of antineoplastic drugs.

THIAZOLE DERIVATIVES AND USE THEREOF

The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.

SYNTHESIS OF DERIVATIVES OF 3-OXOBUTANAL CONTAINING FUNCTIONAL GROUPS IN THE MESOMETHYLENE UNIT

The synthesis of 2-bromo-3-oxobutanal was realized by the bromination of 1-dialkylamino-1-buten-3-ones.The trans-enol form predominates in solutions.The direct nitration of 1,1-diethoxy-3-butanol leads to 2-nitro-3-oxobutanal.