1809272-85-2 Usage
Uses
2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.
Check Digit Verification of cas no
The CAS Registry Mumber 1809272-85-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,9,2,7 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1809272-85:
(9*1)+(8*8)+(7*0)+(6*9)+(5*2)+(4*7)+(3*2)+(2*8)+(1*5)=192
192 % 10 = 2
So 1809272-85-2 is a valid CAS Registry Number.
1809272-85-2Relevant articles and documents
A Three-Step Synthesis of Acotiamide for the Treatment of Patients with Functional Dyspepsia
Fu, Kai,Yang, Liu,Wang, Qiu-Fen,Zhan, Fu-Xu,Wang, Bin,Yang, Qian,Ma, Zhi-Jia,Zheng, Geng-Xiu
, p. 2006 - 2011 (2015)
A three-step synthesis of acotiamide is described. The agent is marketed in Japan for treatment of patients with functional dyspepsia. We designed a one-pot method to prepare the key intermediate 5a from 2 via an acyl chloride and amide and then reacted w
