18096-68-9

Basic information

• Product Name: 2-(Hydroxymethyl)indene
• Synonyms: 1H-Indene-2-methanol;2-(Hydroxymethyl)indene;Indene-2-methanol;(1H-Inden-2-yl)Methanol
• CAS NO: 18096-68-9
• Molecular Formula: C₁₀H₁₀O
• Molecular Weight: 146
• Mol File: 18096-68-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 287℃
• Flash Point: 139℃
• Appearance: /
• Density: 1.138
• Storage Temp.: 2-8°C
• PKA: 14.76±0.10(Predicted)
• CAS DataBase Reference: 2-(Hydroxymethyl)indene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Hydroxymethyl)indene(18096-68-9)
• EPA Substance Registry System: 2-(Hydroxymethyl)indene(18096-68-9)

Safety Data

• Hazardous Substances Data: 18096-68-9(Hazardous Substances Data)

Usage

General Description

2-(Hydroxymethyl)indene, also known as 2-indenol, is an organic compound with the chemical formula C10H10O. It is a clear, colorless to pale yellow liquid with a sweet, floral odor. 2-(Hydroxymethyl)indene is primarily used as an intermediate in the synthesis of other chemicals, such as fragrances and pharmaceuticals. It is also used in the production of insect repellents and flavors. The compound has been shown to have low acute toxicity, but its effects on human health and the environment are still not fully understood. Therefore, proper handling and disposal of 2-(Hydroxymethyl)indene are necessary to minimize potential risks.

Upstream product

• 2177-47-1 2-Methylindene 
• 83-33-0 inden-1-one 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 100188-67-8 ethyl 1-hydroxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate 
• 612-12-4 o-Xylylene dichloride 
• 184423-26-5 2-Benzenesulfonyl-indan-2-carboxylic acid methyl ester 
• 17332-04-6 methyl 2-indenecarboxylate 
• 22955-77-7 methyl 1-indanone-2-carboxylate 
• 6742-26-3 2-ethoxycarbonyl-1-tetralone 

Downstream Products

• 18096-66-7 2-1H-Indenylmethylacetat 
• 168640-24-2 1,2-bis(3-benzylinden-2-yl)ethane 
• 239807-28-4 1,2-bis[(3-phenyl)-2-indenyl]ethane 
• 239807-43-3 tert-butyl-dimethyl-(3-phenyl-1H-inden-2-ylmethoxy)-silane 
• 239807-21-7 3-benzyl-2-(hydroxymethyl)indene 
• 239807-23-9 2-(hydroxymethyl)-3-phenylindene 

Relevant articles and documents

Immunomodulator

The invention discloses an immunomodulator, and particularly relates to compounds for inhibiting IL-17A and application of the compounds serving as the immunomodulator in preparation of drugs. The invention discloses an application of a compound shown as a formula I or a stereoisomer thereof in preparing medicines for inhibiting IL-17A, and provides a new choice for clinically screening and/or preparing medicines for treating diseases related to IL-17A activity.

Immunomodulator

The invention discloses an immunomodulator, and particularly relates to a compound shown as a formula I, or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. Experiments prove that the compound has good IL-17A inhibitory activity, can be used for preparing an IL-17A inhibitor and drugs for preventing and/or treating IL-17A mediated diseases (such as inflammation, autoimmune diseases, infectious diseases, cancers and precancerous syndromes), and provides a new medical possibility for clinical treatment of diseases related to abnormal IL-17A activity.

MONOAMINE RE-UPTAKE INHIBITORS AND METHODS RELATING THERETO

Monoamine re-uptake inhibitors and more specifically serotonin and noradrenaline re-uptake inhibitors are disclosed that have utility in the treatment of disorders of the central or peripheral nervous system in both men and women. The compounds of this invention have the structure: wherein R1, R2, R3, R4, R5, R6, m, n, W, X, Y, and Z are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts, esters and solvates thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting monoamine re-uptake in a subject in need thereof.