22955-77-7

Basic information

• Product Name: Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate
• Synonyms: Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate;methyl 3-oxo-1,2-dihydroindene-2-carboxylate
• CAS NO: 22955-77-7
• Molecular Formula: C₁₁H₁₀O₃
• Molecular Weight: 190.1953
• Mol File: 22955-77-7.mol
• Article Data: 63

Chemical Properties

• Melting Point: 59-60 °C
• Boiling Point: 297.454 °C at 760 mmHg
• Flash Point: 130.012 °C
• Appearance: /
• Density: 1.246 g/cm³
• Vapor Pressure: 0.00135mmHg at 25°C
• Refractive Index: 1.562
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 10.34±0.20(Predicted)
• CAS DataBase Reference: Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate(22955-77-7)
• EPA Substance Registry System: Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate(22955-77-7)

Safety Data

• Hazardous Substances Data: 22955-77-7(Hazardous Substances Data)

Usage

General Description

Methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate is a chemical compound with the molecular formula C12H10O3. It's categorized under the chemical class called coumarins and derivatives. These are polycyclic aromatic compounds containing a 6,8-dihydro-6-oxo-2H-chromene moiety with a methyl substituent at the 2 position. There is limited information available on its physical properties or its uses, but like many similar compounds, it may have applications in organic synthesis or as a precursor for the synthesis of other chemicals. Its exact safety and handling requirements aren't publicly available, so it should be treated with standard lab precautions.

InChI:InChI=1/C11H10O3/c1-14-11(13)9-6-7-4-2-3-5-8(7)10(9)12/h2-5,9H,6H2,1H3

Upstream product

• 67-56-1 methanol 
• 61402-25-3 2-(bis-methylsulfanyl-methylene)-indan-1-one 
• 63600-27-1 2-((E)-2-Methoxycarbonyl-vinyl)-benzoic acid methyl ester 
• 501-52-0 3-Phenylpropionic acid 
• 645-45-4 hydrocinnamic acid chloride 
• 6258-66-8 (4-chlorophenyl)methanethiol 
• 34288-40-9 2-(E)-[2-methoxycarbonylphenyl]acrylic acid methylester 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 103-25-3 3-phenylpropanoic acid methyl ester 
• 103-26-4 methyl cinnamate 
• 36919-03-6 methyl pentafluorophenyl carbonate 
• 83-33-0 inden-1-one 
• 135-19-3 β-naphthol 
• 18454-53-0 (E)-o-carboxycinnamic acid 

Downstream Products

• 343860-68-4 C₂₈H₂₄N₂O₆S 
• 72181-95-4 methyl 2-methyl-1-oxo-2,3-dihydro-1H-indene-2-carboxylate 
• 100461-78-7 1-methoxy-2-(methoxycarbonyl)-1-indene 
• 111170-67-3 2-sec-butyl-2-(methoxycarbonyl)-1-indanone 
• 100461-75-4 methyl 2-ethyl-1-oxo-2,3-dihydro-1H-indene-2-carboxylate 
• 100461-79-8 1-ethoxy-2-(methoxycarbonyl)-1-indene 
• 100461-76-5 2-isopropyl-2-(methoxycarbonyl)-1-indanone 
• 100461-80-1 1-(isopropyloxy)-2-(methoxycarbonyl)-1-indene 
• 111170-67-3 2-((R)-sec-Butyl)-1-oxo-indan-2-carboxylic acid methyl ester 
• 100461-77-6 methyl 2-benzyl-1-oxo-2,3-dihydro-1H-indene-2-carboxylate 
• 100461-81-2 3-Benzyloxy-1H-indene-2-carboxylic acid methyl ester 
• 111170-60-6 2-((R)-1-Methyl-heptyl)-1-oxo-indan-2-carboxylic acid methyl ester 
• 111170-64-0 3-(1-Methyl-heptyloxy)-1H-indene-2-carboxylic acid methyl ester 
• 4254-32-4 indan-2-carboxylic acid methyl ester 

Relevant articles and documents

Diastereoselective intramolecular Ritter reaction: generation of a cis-fused hexahydro-4aH-indeno[1,2-b]pyridine ring system with 4a,9b-diangular substituents.

Indanol intermediates 5, prepared via Michael addition of 1-indanone beta-ketoester and acrylonitrile followed by reduction or Grignard reaction of the ketone group, were submitted to intramolecular Ritter reaction using various acid reaction conditions t

Enantioselective electrophilic trifluoromethylthiolation of β-ketoesters: A case of reactivity and selectivity bias for organocatalysis

A chiral Lewis base or a phase-transfer catalyst (PTC) can mediate the highly enantioselective trifluoromethylthiolation of β-ketoesters with the previously developed SCF3 reagent (see scheme). Reactions of indanone-derived β-ketoesters occurre

Photo-organocatalytic enantioselective perfluoroalkylation of β-ketoesters

The visible-light-driven, phase-transfer-catalyzed, enantioselective perfluoroalkylation and trifluoromethylation of cyclic β-ketoesters is described. The photo-organocatalytic process, which occurs at ambient temperature and under visible light illumination, is triggered by the photochemical activity of in situ-generated electron donor-acceptor complexes, arising from the association of chiral enolates and perfluoroalkyl iodides. Preliminary mechanistic studies are reported.

Electrochemical α-thiolation and azidation of 1,3-dicarbonyls

A highly efficient electrochemical α-thiolation and azidation of 1,3-dicarbonyl compounds is developed. This electrochemical process is conducted under mild conditions without the use of a chemical oxidant, and exhibits a wide scope with good functional g

Tosyloxybenziodoxolone: A Platform for Performing the Umpolung of Alkynes in One-Pot Transformations

Ethynylbenziodoxolones (EBXs) are commonly encountered reagents for the electrophilic alkynylation of nucleophiles. Herein, we report a one-pot, two-step process for EBX generation and their direct application in substrate functionalization. Our approach enables us to bypass the originally mandatory isolation and purification of the reagents, resulting in a more efficient synthesis. We could apply this process to seven different transformations involving both two- and one-electron nucleophiles to obtain a large variety of alkynylated products.

APPLICATION OF METAL HYDRIDE/PALLADIUM COMPOUND SYSTEM IN PREPARATION OF 1,3-DICARBONYL COMPOUND IN CASCADE REACTION OF ELECTRON-DEFICIENT ALKENE COMPOUND

Provided is an application of a metal hydride/palladium compound system in the preparation of a 1,3-dicarbonyl compound in a cascade reaction of an electron-deficient alkene compound, said reaction comprising the following steps: under the protection of n