18100-80-6

Basic information

• Product Name: 2,3,5-triphenyl-4-thiazolone
• Synonyms: 2,3,5-triphenyl-4-thiazolone
• CAS NO: 18100-80-6
• Molecular Weight: 329.422
• Mol File: 18100-80-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,3,5-triphenyl-4-thiazolone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5-triphenyl-4-thiazolone(18100-80-6)
• EPA Substance Registry System: 2,3,5-triphenyl-4-thiazolone(18100-80-6)

Safety Data

• Hazardous Substances Data: 18100-80-6(Hazardous Substances Data)

Upstream product

• 19078-72-9 bromo(phenyl)acetyl chloride 
• 62-53-3 aniline 
• 39982-78-0 α-bromophenylacetanilide 
• 107960-53-2 DL-N,2-Diphenyl-2-<(thiobenzoyl)thio>acetamid 
• 4870-65-9 2-bromophenylacetic acid 
• 636-04-4 thiobenzanilide 
• 636-04-4 N-Phenylbenzothioamide 
• 33512-02-6 3-phenyl-2,2-oxiranedicarbonitrile 

Downstream Products

• 52731-18-7 2,4,5,7-tetraphenyl-(3ac,7ac)-tetrahydro-4r,7c-episulfano-pyrrolo[3,4-c]pyridine-1,3,6-trione 
• 52748-26-2 6-methyl-3-oxo-1,2,4-triphenyl-7-thia-2-aza-bicyclo[2.2.1]heptane-6endo-carboxylic acid ethyl ester 
• 52731-11-0 5exo-methyl-3-oxo-1,2,4-triphenyl-7-thia-2-aza-bicyclo[2.2.1]heptane-6endo-carboxylic acid ethyl ester 
• 52748-27-3 5exo,6endo-dibenzoyl-1,2,4-triphenyl-7-thia-2-aza-bicyclo[2.2.1]heptan-3-one 
• 113326-97-9 C₂₆H₂₅N₃O₆S 
• 138813-49-7 (1S*,4S*,5S*,5'S*)-1',5'-dihydro-5'-morpholino-1'-(4-nitrophenyl)-3-oxo-1,2,4-triphenylspiro<7-thia-2-azabicyclo<2.2.1>heptane-5,4'-<4H><1,2,3>triazole> 
• 138876-01-4 (1S*,4S*,5R*,5'R*)-1',5'-dihydro-5'-morpholino-1'-(4-nitrophenyl)-3-oxo-1,2,4-triphenylspiro<7-thia-2-azabicyclo<2.2.1>heptane-5,4'-<4H><1,2,3>triazole> 
• 95702-60-6 2,3-diphenylquinolin-4-ol 
• 61923-94-2 3,10syn-dioxo-1,2,4-triphenyl-9-(toluene-4-sulfonyl)-(4at,8at)-1,2,3,4,4a,5,8,8a-octahydro-10λ⁴-5c,8c-epiazano-1r,4c-episulfano-isoquinoline-6,7-dicarboxylic acid dimethyl ester 
• 18100-89-5 Thiobenzoic acid S-(phenyl-phenylcarbamoyl-methyl) ester 
• 62616-06-2 3,9syn-oxo-1,2,4-triphenyl-(4at,4bc,8ac,8bt)-1,2,3,4,4a,4b,5,8,8a,8b-decahydro-9λ⁴-1r,4c-episulfano-5t,8t-etheno-benzo[3,4]cyclobuta[1,2-c]pyridine-6,7-dicarboxylic acid dimethyl ester 
• 62616-08-4 9anti-oxo-1,6,7-triphenyl-(1rS,2tH,5tH,6cS)-9λ⁴-thia-7-aza-tricyclo[4.2.1.0^2,5]non-3-en-8-one 
• 62616-04-0 1,6,7-triphenyl-(1rS,2tH,5tH,6cS)-9-thia-7-aza-tricyclo[4.2.1.0^2,5]non-3-en-8-one 
• 52731-20-1 5exo,6endo-dibenzoyl-7-oxo-1,2,4-triphenyl-7λ⁴-thia-2-aza-bicyclo[2.2.1]heptan-3-one 

Relevant articles and documents

Bioorthogonal Click and Release Reaction of Iminosydnones with Cycloalkynes

We report the discovery of a new bioorthogonal click-and-release reaction involving iminosydnones and strained alkynes. This transformation leads to two products resulting from the ligation and fragmentation of iminosydnones under physiological conditions. Optimized iminosydnones were successfully used to design innovative cleavable linkers for protein modification, thus opening up new areas in the fields of drug release and target-fishing applications. This click-and-release technology offers the possibility of exchanging tags on proteins for functionalized cyclooctynes under mild and bioorthogonal conditions.

Antitrichomonal Activity of Mesoionic Thiazolopyridines

Screening of mesoionic compounds as potential electron acceptors by analogy with metronidazole led to the finding of in vitro antitrichomonal activity for anhydro-2-phenyl-3-hydroxythiazolopyridinium hydroxide (1).In a series of analogues, potent i