18102-30-2Relevant articles and documents
Total synthesis of the isoquinolinium metabolite ETM-204 of Trabectidin
Breinbauer, Rolf,Gissing, Simon,Lembacher-Fadum, Christian,Pour, Georg
, (2021/10/23)
Ecteinascidin-743 (Trabectidin, Trabectedin, Yondelis) is a synthetically obtained pharmaceutical drug originally isolated from a marine tunicate. Trabectedin is used for the chemotherapy of soft-tissue sarcoma and ovarian cancer. Th
COUMARIN DERIVATIVES AND METHODS OF USE IN TREATING CYSTIC FIBROSIS, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, AND MISFOLDED PROTEIN DISORDERS
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Page/Page column 55, (2014/10/04)
Novel CFTR corrector compounds that are effective in rescuing halide efflux, delF508-CFTR protein processing, and apical functional chloride ion transport in a cell are provided. Also provided are methods for treating protein folding disorders (e.g., cyst
Amination of arenes with N,N-dimethyl-2-imidazolidinone O-methoxyacetyloxime
Baldovini, Nicolas,Kitamura, Mitsuru,Narasaka, Koichi
, p. 548 - 549 (2007/10/03)
Treatment of nucleophilic arenes with N,N-dimethyl-2imidazolidinone O-methoxyacetyloxime and SnCl4 produced the corresponding N-arylimines, which were converted to anilines by hydrolysis with CsOH and to N-methylanilines by LiAlH4 reduction.