181419-93-2

Upstream product

• 556-56-9 allyl iodid 
• 115437-18-8 7-triethylsilyl-10-deacetylbaccatin III 

Downstream Products

• 181419-96-5 1-O-allyl-13-O-[(2R,3S)-3-(tert-butoxycarbonylamino)-3-phenyl-2-(triethylsilyloxy)propionyl]-10-deacetyl-7-O-triethylsilylbaccatin III 
• 181420-02-0 13-O-[(2R,3S)-3-(tert-butoxycarbonylamino)-3-phenyl-2-(triethylsilyloxy)propionyl]-10-deacetyl-10-O-formylmethyl-7-O-triethylsilylbaccatin 
• 181420-07-5 C₆₁H₉₂N₂O₁₅Si₂ 
• 181421-40-9 C₆₁H₉₂N₂O₁₄SSi₂ 

Relevant academic research and scientific papers

Synthesis and evaluation of water-soluble non-prodrug analogs of docetaxel bearing sec-aminoethyl group at the C-10 position

To develop non-prodrugs of taxoids with satisfactory stability in vivo, high water-solubility, and potent antitumor activity, we prepared several 10- O-sec-aminoethyl docetaxel analogs (3) and evaluated their cytotoxicity against mouse leukemia and human