1814901-03-5 Usage
Uses
Used in Bioconjugation:
NH-(PEG3-t-butyl ester)2 is used as a bioconjugation agent for the formation of stable covalent bonds between biomolecules and other molecules, such as drugs or imaging agents. The reactive amino group allows for easy attachment to carboxylic acid-containing molecules, while the PEG units provide solubility and stability to the final conjugate.
Used in Drug Delivery Systems:
In the pharmaceutical industry, NH-(PEG3-t-butyl ester)2 is used as a component in drug delivery systems for improving the solubility, stability, and bioavailability of therapeutic agents. The PEG units in the molecule can enhance the circulation time of drugs in the body, while the reactive amino group allows for the attachment of drug molecules to the delivery system.
Used in Diagnostic Imaging:
NH-(PEG3-t-butyl ester)2 is used as a contrast agent in diagnostic imaging applications, such as magnetic resonance imaging (MRI) and computed tomography (CT). The PEG units in the molecule can improve the solubility and stability of imaging agents, while the reactive amino group allows for the attachment of imaging agents to targeting molecules for enhanced imaging contrast.
Used in Material Science:
In the field of material science, NH-(PEG3-t-butyl ester)2 is used as a building block for the development of novel materials with specific properties. The reactive amino group and PEG units can be utilized to create self-assembling structures or to modify the surface properties of materials for various applications, such as drug release, tissue engineering, or sensor development.
Used in Chemical Synthesis:
NH-(PEG3-t-butyl ester)2 is used as an intermediate in the synthesis of complex organic molecules, such as pharmaceuticals, agrochemicals, and specialty chemicals. The reactive amino group and t-butyl protected carboxyl group provide opportunities for further functionalization and modification of the molecule, enabling the development of new compounds with desired properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1814901-03-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,1,4,9,0 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1814901-03:
(9*1)+(8*8)+(7*1)+(6*4)+(5*9)+(4*0)+(3*1)+(2*0)+(1*3)=155
155 % 10 = 5
So 1814901-03-5 is a valid CAS Registry Number.
1814901-03-5Relevant academic research and scientific papers
CROSS-LINKED PYRROLOBENZODIAZEPINE DIMER (PBD) DERIVATIVE AND ITS CONJUGATES
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, (2020/01/31)
A novel cross-linked cytotoxic agents, pyrrolobenzo-diazepine dimer (PBD) derivatives, and their conjugates to a cell-binding molecule, a method for preparation of the conjugates and the therapeutic use of the conjugates.
CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE
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, (2020/01/08)
What provided is the conjugation of cytotoxic to a cell-binding molecule with a bis-linker(dual-linker) as shown in Formula (I). It provides bis-linkage methods of making a conjugate of a cytotoxic drug molecule to a cell-binding agent in a specific manner. It also relates to application of the conjugates for the treatment of a cancer, or an autoimmune disease, or an infectious disease.
