181872-29-7

Upstream product

• 181872-28-6 N-{(R)-[(2S)-1-((1R)-2-hydroxy-1-phenylethyl)piperidin-2-yl]phenylmethyl}benzamide 
• 88056-92-2 (-)-2-cyano-6-phenyloxazolopiperidine 
• 181872-19-5 (2R)-2-phenyl-2-((1S,5S)-7-phenyl-6,8-diazabicyclo[3.2.1]oct-6-en-8-yl)ethanol 
• 181872-21-9 (1S,4R,9aS)-1,4-Diphenyl-octahydro-pyrido[2,1-c][1,4]oxazin-1-ylamine 
• 181872-24-2 (2R)-2-{(2S)-2-[(R)-(1-aminophenyl)methyl]piperidin-1-yl}-2-phenylethanol 
• 591-51-5 phenyllithium 
• 98-88-4 benzoyl chloride 

Relevant academic research and scientific papers

Asymmetric synthesis. 39. Synthesis of 2-(1-aminoalkyl)piperidines via 2-cyano-6-phenyl oxazolopiperidine

The asymmetric synthesis of a series of 2-(1-aminoalkyl) piperidines using (-)-2-cyano-6-phenyloxazolopiperidine 1 is described. LiAlH4 reduction of 1 followed by hydrogenolysis led to the diamine 3. The same strategy applied to C-2-methylated