18227-66-2 Usage
Uses
Used in Pharmaceutical Industry:
3-Methyl-N-nitropyridin-4-aMine is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a building block for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Methyl-N-nitropyridin-4-aMine is utilized as a precursor in the production of agrochemicals. Its properties contribute to the creation of compounds that can be used in pest control and crop protection, enhancing agricultural productivity.
Used in Dye Industry:
3-Methyl-N-nitropyridin-4-aMine is employed as a chemical intermediate in the synthesis of dyes. Its incorporation into dye molecules results in a range of colors and properties suitable for various applications, including textiles, plastics, and printing inks.
Used in Organic Compounds Production:
As an intermediate, 3-Methyl-N-nitropyridin-4-aMine is crucial in the production of other organic compounds. Its versatility in chemical reactions enables the creation of a diverse array of organic molecules for use in various industries and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 18227-66-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,2,2 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 18227-66:
(7*1)+(6*8)+(5*2)+(4*2)+(3*7)+(2*6)+(1*6)=112
112 % 10 = 2
So 18227-66-2 is a valid CAS Registry Number.
18227-66-2Relevant academic research and scientific papers
The synthesis of anti-fixed 3-methyl-3-deaza-2′-deoxyadenosine and other 3h-imidazo[4,5-c]pyridine analogs
Irani, Rostem J.,SantaLucia Jr., John
, p. 737 - 751 (2007/10/03)
Rotation of a heterocyclic base around a glycosidic bond allows the formation of syn and anti conformations in nucleosides. The syn conformation has been observed primarily in purine-purine mismatches in DNA duplexes. Such mismatches give rise to false positive oligonucleotide hybridization in DNA-based diagnostics. Here we describe the synthesis of an analog of 2′-deoxyadenosine that retains its Watson-Crick functional groups, but cannot form the syn conformation. In this analog, the N3 atom of 2′-deoxyadenosine is replaced by a C-CH3 group to give 7-methyl-1-β-D-deoxyribofuranosyl-1H-imidazo[4,5-c]pyridin-4-ylamine or 3-methyl-3-deaza-2′-deoxyadenosine (3mddA). This modification sterically prevents the syn conformation and 3mddA becomes an anti-fixed nucleoside analog of 2′-deoxyadenosine. The synthesis and conformational analysis of 3mddA and several analogs with an 3H-imidazo[4,5-c]pyridine skeleton are described, as well as their potential applications.
