18229-17-9

Basic information

• Product Name: 8-hydroxytetradecan-7-one
• Synonyms: 8-hydroxytetradecan-7-one;8-Hydroxy-7-tetradecanone;Einecs 242-109-8
• CAS NO: 18229-17-9
• Molecular Formula: C₁₄H₂₈O₂
• Molecular Weight: 228.37092
• EINECS: 242-109-8
• Mol File: 18229-17-9.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 263.2 °C at 760 mmHg
• Flash Point: 109.3 °C
• Appearance: /
• Density: 0.896g/cm³
• Vapor Pressure: 0.00147mmHg at 25°C
• Refractive Index: 1.45
• CAS DataBase Reference: 8-hydroxytetradecan-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-hydroxytetradecan-7-one(18229-17-9)
• EPA Substance Registry System: 8-hydroxytetradecan-7-one(18229-17-9)

Safety Data

• Hazardous Substances Data: 18229-17-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H28O2/c1-3-5-7-9-11-13(15)14(16)12-10-8-6-4-2/h13,15H,3-12H2,1-2H3

Upstream product

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Relevant articles and documents

Carbonylation of dialkylcyanocuprates with carbon monoxide: Synthesis of α-hydroxyketones

Dialkylcyanocuprates, prepared from copper(I) cyanide and the corresponding alkyllithium or Gringard reagents, readily react with carbon monoxide in the presence of tri-n-butylphosphine at -78°C in THF to give α-hydroxyketones in high yields (65-85%).

NOVEL PROCESS FOR PREPARING SYNTHESIS INTERMEDIATES USING PRODUCTS OF NATURAL ORIGIN AND USE OF THE INTERMEDIATES OBTAINED

Disclosed is a process for preparing a product of formula I: wherein the reaction is catalyzed both by thiamine or a thiamine salt and by ascorbic acid in a form which is free or salified or an organic acid salt of an alkaline metal, preferably sodium acetate, potassium tartrate, sodium succinate, or a reductone, preferably 2-hydroxypropanedial or 2,3-dihydroxycyclopent-2-ene-1-one in an organic solvent.

Tandem hydroformylation/acyloin reaction - The synergy of metal catalysis and organocatalysis yielding acyloins directly from olefins

A novel, atom efficient, orthogonal tandem catalysis was developed yielding acyloin products (α-hydroxy ketones) directly from olefins under hydroformylation conditions. The combination of a metal-catalysed hydroformylation and an organocatalysed acyloin reaction provides three atom efficient C-C bond formations to linear, multifunctional molecules via linkage of the intermediate n-aldehydes. Additionally, the rhodium catalyst system gives a high n/bra ratio with an exclusive conversion of the terminal double bond in the hydroformylation and the n-aldehydes are converted selectively to their acyloins.