182422-50-0

Upstream product

• 2212-75-1 N₂-[(benzyloxy)carbonyl]-L-lysine 
• 64-19-7 acetic acid 
• 127623-77-2 tert-butyl (S)-2-benzyloxycarbonylamino-6-hydroxyhex-5-enoate 
• 1218782-07-0 methyl (2S)-2-([(benzyloxy)carbonyl]amino)hex-5-enoate 
• 1032591-95-9 (S)-benzyl 1-hydroxyhex-5-en-2-ylcarbamate 
• 606148-69-0 (S)-2-[(1R,2R,5R)-2-Hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-(3E)-ylideneamino]-hex-5-enoic acid tert-butyl ester 
• 606148-70-3 tert-butyl (2S)-2-aminohex-5-enoate 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 241161-72-8 ethyl N-benzyloxycarbonyl-L-2-amino-5-hexenoate 
• 441353-27-1 (2S,5S)-2-benzyloxycarbonylamino-5-iodomethyl-δ-valerolactone 
• 441353-26-0 (2S,5R)-2-benzyloxycarbonylamino-5-iodomethyl-δ-valerolactone 
• 875574-96-2 (S)-methyl 2-((R)-2-(benzyloxycarbonylamino)hex-5-enamido)-5-(1,3-dioxolan-2-yl)pentanoate 
• 309928-95-8 (2S,5S)-5-azidomethyl-2-benzyloxycarbonylamino-δ-valerolactone 
• 102108-01-0 (2S,5R)-1-(benzyloxycarbonyl)-5-(hydroxymethyl)pyrrolidine-2-carboxylic acid 
• 1443768-79-3 (4aS,9aS)-N-benzyloxycarbonyl-4,4a,5,8,9,9a-hexahydro-2H-cyclohepta[d][1,3]oxazinan-4-one 
• 1443769-18-3 (1S,2S)-N-benzyloxycarbonyl-2-methylaminocycloheptane carboxylic acid 
• 1443768-93-1 phenylmethyl N-[(3S)-1-diazo-2-oxohept-6-en-3-yl]carbamate 
• 1443768-97-5 (3S)-3-{[(benzyloxy)carbonyl]amino}hept-6-enoic acid 
• 1443768-71-5 N-benzyloxycarbonyl-4-(but-3-en-1-yl)-1,3-oxazinan-6-one 
• 1443768-74-8 (4S,5S)-N-benzyloxycarbonyl-4-but-3-enyl-5-allyl-1,3-oxazinan-6-one 
• 1443769-03-6 (4S)-N-benzyloxycarbonyl-4-but-3-enyl-5,5-diallyl-1,3-oxazinan-6-one 
• 1443769-07-0 (4S)-N-benzyloxycarbonyl-4-but-3-enyl-5,5-di(2-methylallyl)-1,3-oxazinan-6-one 

Relevant academic research and scientific papers

Diastereoselective synthesis of cyclic β2,3-amino acids utilizing 4-substituted-1,3-oxazinan-6-ones

The 4-substituted-1,3-oxazinan-6-one scaffold is a versatile synthon enabling access to a diverse array of β-amino acid derivatives. In this study, the synthetic utility of the 1,3-oxazinan-6-one is expanded to include the diastereoselective synthesis of

Syntheses and biological activity of amamistatin B and analogs

(Chemical Equation Presented) Amamistatins A and B, natural products isolated from a strain of Nocardia, showed growth inhibition against three human tumor cell lines (IC50 0.24-0.56 μM). Structurally related mycobactins affect the growth of bo

Pyridine-N-oxide as a mild reoxidant which transforms osmium-catalyzed oxidative cyclization

(Chemical Equation Presented) The PNOman can: The use of pyridine-N-oxide (PNO) transforms the catalytic oxidative cyclization to include the formation of pyrrolidines from N-Z-protected amino alcohols and amino acids (see scheme; Z = PhCH2OCO). This new method expands the scope of the oxidative cyclization as illustrated with the synthesis of a range of di- and trisubstituted pyrrolidines with complete control of stereochemistry.

N-METHYL AMINO ACIDS

The present invention relates to a compound of formula (I) or (II), processes for preparing them, peptides including them and kits involving them.

A simple modular synthesis of pyridinoline a collagen cross-link of biochemical interest

A simple convergent synthesis of the collagen cross-link pyridinoline starting from glycine is reported.

Stereospecific synthesis of the anaesthetic levobupivacaine

Enantiomerically pure (S)-bupivacaine is synthesized from the chiral pool using cheap and readily available (S)-lysine. The key steps in this efficient synthesis include an oxidative de-amination and stereospecific ring closure to form the pipecolamide core structure.