1829-25-0

Basic information

• Product Name: 1-Methoxy-1,2-benziodoxol-3-(1H)-one
• Synonyms: 1-Methoxy-1,2-benziodoxol-3-(1H)-one
• CAS NO: 1829-25-0
• Molecular Formula: C₈H₇IO₃
• Molecular Weight: 278.04385
• Mol File: 1829-25-0.mol
• Article Data: 16

Chemical Properties

• Melting Point: 164-168 °C
• Appearance: /
• CAS DataBase Reference: 1-Methoxy-1,2-benziodoxol-3-(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methoxy-1,2-benziodoxol-3-(1H)-one(1829-25-0)
• EPA Substance Registry System: 1-Methoxy-1,2-benziodoxol-3-(1H)-one(1829-25-0)

Safety Data

• Hazardous Substances Data: 1829-25-0(Hazardous Substances Data)

Usage

Chemical compound

1-Methoxy-1,2-benziodoxol-3-(1H)-one is a chemical compound.

Appearance

It is a white solid.

Use as a reagent

It is commonly used as a hypervalent iodine reagent in organic synthesis.

Electrophilic iodinating agent

1-Methoxy-1,2-benziodoxol-3-(1H)-one is known for its ability to act as an electrophilic iodinating agent.

Chemical reactions

It is useful for various chemical reactions, including halogenations, oxidations, and functional group transformations.

Preparation of organic molecules

1-Methoxy-1,2-benziodoxol-3-(1H)-one is often utilized in the preparation of organic molecules.

Value in synthetic chemistry

It is considered a valuable tool in synthetic chemistry.

Stability and reactivity

The methoxy group in the compound provides stability and enhanced reactivity, making it a versatile reagent for a wide range of applications in organic synthesis.

Upstream product

• 1829-26-1 1-acetoxy-1,2-benziodoxol-3-one 
• 124-41-4 sodium methylate 
• 67-56-1 methanol 
• 142260-70-6 1-(tert-butylperoxy)-1,2-benziodoxol-3(1H)-one 
• 59457-26-0 1-chloro-1λ³-benzo[d][1,2]iodaoxol-3(1H)-one 
• 61717-82-6 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione 
• 88-67-5 2-Iodobenzoic acid 
• 131-62-4 1-hydroxy-1,2-benzodioxol-3-(1H)-one 
• 87413-09-0 Dess-Martin periodane 
• 155791-59-6 Phosphoric acid 3-oxo-3H-1λ³-benzo[d][1,2]iodoxol-1-yl ester diphenyl ester 

Downstream Products

• 947-84-2 2-Biphenylcarboxylic acid 
• 887144-94-7 Togni's reagent II 
• 1825-61-2 Trimethylmethoxysilane 
• 65880-87-7 3,3-bis(methylthio)-2-methoxy-1-phenylprop-2-en-1-one 
• 131-62-4 1-hydroxy-1,2-benzodioxol-3-(1H)-one 

Relevant articles and documents

CHEMISTRY OF AN ACYLOXYIODINANE, THE INTERMEDIATE IN IODOSOBENZOATE CATALYZED CLEAVAGE OF ACTIVE ESTERS

The 1-acetoxy-1,2-benziodoxol-3(1H)-one intermediate in the o-iodosobenzoate cleavage of p-nitrophenyl acetate can be directly observed in dimethyl sulfoxide.

1,3-Oxyalkynylation of Aryl Cyclopropanes with Ethylnylbenziodoxolones Using Photoredox Catalysis

Alkynes and cyclopropanes are vital motifs in chemistry. Herein, a photoredox catalyzed 1,3-oxyalkynylation of aryl cyclopropanes with ethylnylbenziodoxolones (EBXs) in an atom-economic fashion is described. This cascade comprises single-electron oxidatio

Practical synthesis of 2-iodosobenzoic acid (IBA) without contamination by hazardous 2-iodoxybenzoic acid (IBX) under mild conditions

We report a convenient and practical method for the preparation of nonexplosive cyclic hypervalent iodine(III) oxidants as efficient organocatalysts and reagents for various reactions using Oxone in aqueous solution under mild conditions at room temperature. The thus obtained 2-iodosobenzoic acids (IBAs) could be used as precursors of other cyclic organoiodine(III) derivatives by the solvolytic derivatization of the hydroxy group under mild conditions of 80 °C or lower temperature. These sequential procedures are highly reliable to selectively afford cyclic hypervalent iodine compounds in excellent yields without contamination by hazardous pentavalent iodine(III) compound.