182953-77-1Relevant articles and documents
Synthesis of curacin A, an antimitotic cyclopropane-thiazoline from the marine cyanobacterium Lyngbya majuscula
Lai, Jing-Yu,Yu, Jurong,Mekonnen, Belew,Falck
, p. 7167 - 7170 (1996)
Charette asymmetric cyclopropanation, chiral thiazoline synthesis by thioamide cyclization under modified Mitsunobu conditions, Ti(iPrO)4/bi-naphthol catalyzed allylstannane addition, and an exceptionally mild two-carbon homologation via dehydrative alkylation with phenylsulfonylacetonitrile/Ph3P/ADDP convened in an efficient, stereocontrolled route to the title bioactive heterocycle.