1832-64-0Relevant academic research and scientific papers
The influence of hydrophobic amines on hydrolysis of bis(p-nitrophenyl) methylphosphonate in micellar solutions of cetylpyridinium bromide
Mirgorodskaya,Kudryavtseva,Zuev,Archipov,Idiyatullin,Kudryavtsev
, p. 270 - 275 (2000)
The kinetics of hydrolysis of bis(p-nitrophenyl) methylphosphonate in the presence of primary aliphatic amines in aqueous micellar solutions of cetylpyridinium bromide was studied. The reaction proceeds via two routes, alkaline hydrolysis and amine-cataly
Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily
Van Loo, Bert,Bayer, Christopher D.,Fischer, Gerhard,Jonas, Stefanie,Valkov, Eugene,Mohamed, Mark F.,Vorobieva, Anastassia,Dutruel, Celine,Hyv?nen, Marko,Hollfelder, Florian
supporting information, p. 370 - 387 (2019/01/08)
Highly proficient, promiscuous enzymes can be springboards for functional evolution, able to avoid loss of function during adaptation by their capacity to promote multiple reactions. We employ a systematic comparative study of structure, sequence, and sub
Synthesis and anti-acetylcholinesterase properties of novel β- And γ-substituted alkoxy organophosphonates
Kaleem Ahmed,Belabassi, Yamina,Sankaranarayanan, Lakshmi,Chao, Chih-Kai,Gerdes, John M.,Thompson, Charles M.
, p. 2048 - 2051 (2013/04/23)
Activated organophosphate (OP) insecticides and chemical agents inhibit acetylcholinesterase (AChE) to form OP-AChE adducts. Whereas the structure of the OP correlates with the rate of inhibition, the structure of the OP-AChE adduct influences the rate at
CHOLINESTERASE INHIBITORS
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Paragraph 0142, (2014/02/15)
The invention provides compounds that inhibit cholinesterases, such as acetylcholinesterase and butyrylcholinesterase. Such compounds are useful to prevent or treat exposure of a patient (e.g., a human) to an organophosphoric nerve agent (e.g., sarin and
Catalysis of the hydrolysis of esters of phosphorus acids by n-decylammonium chloride/n-decylamine mixed micelles
Bakeeva,Kudryavtseva,Bel'skii,Fedorov,Ivanov
, p. 1900 - 1903 (2007/10/03)
The effect of n-decylammonium chloride/n-decylamine mixed micelles on the rate of hydrolysis of aryl esters of acids of four-coordinate phosphorus was studied spectrophotometrically. The shape of the concentration curves is characteristic of the micellar
