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O-2-fluoroethyl-O-p-nitrophenyl methyphosphonothionate, also known as sarin, is a highly toxic organophosphorus compound that acts as a potent nerve agent. It is a colorless, odorless, and tasteless liquid, making it difficult to detect. Sarin is a G-series nerve agent, which was developed in Germany during World War II. It inhibits the enzyme acetylcholinesterase, leading to the accumulation of acetylcholine in the nervous system and causing overstimulation of muscles and glands. This results in symptoms such as convulsions, respiratory failure, and eventually death. Sarin is highly volatile and can be absorbed through the skin, inhaled, or ingested, making it a dangerous chemical warfare agent. Due to its extreme toxicity and potential for misuse, sarin is classified as a weapon of mass destruction and is regulated under various international treaties and conventions.

889-14-5

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889-14-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 889-14-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,8 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 889-14:
(5*8)+(4*8)+(3*9)+(2*1)+(1*4)=105
105 % 10 = 5
So 889-14-5 is a valid CAS Registry Number.

889-14-5Relevant academic research and scientific papers

Synthesis and anti-acetylcholinesterase properties of novel β- And γ-substituted alkoxy organophosphonates

Kaleem Ahmed,Belabassi, Yamina,Sankaranarayanan, Lakshmi,Chao, Chih-Kai,Gerdes, John M.,Thompson, Charles M.

, p. 2048 - 2051 (2013/04/23)

Activated organophosphate (OP) insecticides and chemical agents inhibit acetylcholinesterase (AChE) to form OP-AChE adducts. Whereas the structure of the OP correlates with the rate of inhibition, the structure of the OP-AChE adduct influences the rate at

CHOLINESTERASE INHIBITORS

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Paragraph 0147; 0148, (2014/02/15)

The invention provides compounds that inhibit cholinesterases, such as acetylcholinesterase and butyrylcholinesterase. Such compounds are useful to prevent or treat exposure of a patient (e.g., a human) to an organophosphoric nerve agent (e.g., sarin and

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