183788-33-2Relevant academic research and scientific papers
Interphylal product splicing: The first total syntheses of cephalostatin 1, the North hemisphere of ritterazine G, and the highly active hybrid analogue, ritterostatin G(N)1(N)1
LaCour, Thomas G.,Guo, Chuangxing,Bhandaru, Sudhakar,Boyd, Michael R.,Fuchs
, p. 692 - 707 (1998)
Convergent total syntheses of the extremely potent cell growth inhibitor cephalostatin 1 and two hybrid analogues, ritterostatins G(N)1(N) and G(N)1(s), have been achieved. Ritterostatin G(N)1(N) displays sub-nanomolar activity in the 60 cell line human t
Outer-ring stereochemical modulation of cytotoxicity in cephalostatins.
LaCour,Guo,Boyd,Fuchs
, p. 33 - 36 (2007/10/03)
[structure: see text] 20- and 25'-epimers of cephalostatin 7, prepared by directed unsymmetrical pyrazine synthesis, address outer-ring topographical and stability questions and intimate an oxacarbenium ion rationale for the role in bioactivity of the spi
