184001-08-9Relevant articles and documents
Copying nature's mechanism for the decarboxylation of β-keto acids into catalytic antibodies by reactive immunization
Bj?rnestedt, Robert,Zhong, Guofu,Lerner, Richard A.,Barbas III, Carlos F.
, p. 11720 - 11724 (1996)
Reactive immunization was used to generate catalytic antibodies that use the enamine mechanism common to the natural class I aldolase enzymes. In order to investigate the possibility of exploiting the imine and enamine intermediates programmed into antibo
