184036-18-8

Basic information

• Product Name: 3-[N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl]-N-(6-cyano-1,3-benzodioxol-5-yl)thiophene-2-carboxamide
• Synonyms: TBC-11241
• CAS NO: 184036-18-8
• Molecular Formula: C₁₇H₁₁ClN₄O₆S₂
• Molecular Weight: 466.88142
• Mol File: 184036-18-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl]-N-(6-cyano-1,3-benzodioxol-5-yl)thiophene-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl]-N-(6-cyano-1,3-benzodioxol-5-yl)thiophene-2-carboxamide(184036-18-8)
• EPA Substance Registry System: 3-[N-(4-Chloro-3-methylisoxazol-5-yl)sulfamoyl]-N-(6-cyano-1,3-benzodioxol-5-yl)thiophene-2-carboxamide(184036-18-8)

Safety Data

• Hazardous Substances Data: 184036-18-8(Hazardous Substances Data)

Upstream product

• 52805-38-6 6-nitro-1,3-benzodioxole-5-carbonitrile 
• 184040-74-2 3{[(4-chloro-3-methyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxylic acid 
• 184644-72-2 3-{[(4-chloro-3-methyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxylic acid methyl ester 
• 4421-09-4 piperonylonitrile 
• 187164-87-0 5-amino-6-cyanobenzo<1,3>dioxale 

Relevant articles and documents

Structure-activity relationships of N2-aryl-3-(isoxazolylsulfamoyl)-2- thiophenecarboxamides as selective endothelin receptor-A antagonists

We report here that N2-aryl-3-(isoxazolylsulfamoyl)-2- thiophenecarboxamides are potent and selective small molecule ET(A) receptor antagonists. The aryl group was subjected to extensive structural modification. With monosubstitution, the para